Peptide‐mediated interactions (PMIs) play a crucial role in cell signaling network, which are
responsible for about half of cellular protein–protein associations in the human interactome …

Viruses are obligate intracellular parasites that depend on host cellular machinery for
performing even basic biological functions. One of the many ways they achieve this is …

Evolutionary changes in host-virus interactions can alter the course of infection, but the
biophysical and regulatory constraints that shape interface evolution remain largely …

Ehrlichia chaffeensis TRP120 effector has evolved short linear motif (SLiM) ligand mimicry to
repurpose multiple evolutionarily conserved cellular signaling pathways, including Wnt …

Ehrlichia chaffeensis (E. chaffeensis) has evolved eukaryotic ligand mimicry to repurpose
multiple cellular signaling pathways for immune evasion. In this investigation, we …

One of the mechanisms viruses use in hijacking host cellular machinery is mimicking Short
Linear Motifs (SLiMs) in host proteins to maintain their life cycle inside host cells. In the face …

Viruses and their hosts are involved in an 'arms race'where they continually evolve
mechanisms to overcome each other. It has long been proposed that intrinsic disorder …

Cancer remains one of the leading causes of death globally. New immunotherapies that
harness the patient's immune system to fight cancer show promise, but their development …

Effectoromics has become integral to the identification of pathogen targets and/or host-
resistant proteins for the genetic improvement of plants in agriculture and horticulture …

Ehrlichia chaffeensis TRP120 effector has evolved short linear motif (SLiM) ligand mimicry to
repurpose multiple evolutionarily conserved cellular signaling pathways including Wnt …