Advances in spatial transcriptomic data analysis
Spatial transcriptomics is a rapidly growing field that promises to comprehensively
characterize tissue organization and architecture at the single-cell or subcellular resolution …
characterize tissue organization and architecture at the single-cell or subcellular resolution …
Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance
CE Eyler, H Matsunaga, V Hovestadt, SJ Vantine… - Genome biology, 2020 - Springer
Background Tumors can evolve and adapt to therapeutic pressure by acquiring genetic and
epigenetic alterations that may be transient or stable. A precise understanding of how such …
epigenetic alterations that may be transient or stable. A precise understanding of how such …
BRIE2: computational identification of splicing phenotypes from single-cell transcriptomic experiments
Y Huang, G Sanguinetti - Genome biology, 2021 - Springer
RNA splicing is an important driver of heterogeneity in single cells through the expression of
alternative transcripts and as a determinant of transcriptional kinetics. However, the intrinsic …
alternative transcripts and as a determinant of transcriptional kinetics. However, the intrinsic …
Integration of multimodal data in the developing tooth reveals candidate regulatory loci driving human odontogenic phenotypes
E Wentworth Winchester, A Hardy… - Frontiers in dental …, 2022 - frontiersin.org
Human odontogenic aberrations such as abnormal tooth number and delayed tooth eruption
can occur as a symptom of rare syndromes or, more commonly, as nonsyndromic …
can occur as a symptom of rare syndromes or, more commonly, as nonsyndromic …
Single-cell sequencing in human genital infections
R Singh - Single-cell Sequencing and Methylation: Methods and …, 2020 - Springer
Human genital infections are one of the most concerning issues worldwide and can be
categorized into sexually transmitted, urinary tract and vaginal infections. These infections, if …
categorized into sexually transmitted, urinary tract and vaginal infections. These infections, if …
Integration of multimodal data in the developing tooth reveals candidate dental disease genes
EW Winchester, A Hardy, J Cotney - bioRxiv, 2022 - biorxiv.org
Dental malformations range from rare syndromes to common nonsyndromic phenotypes.
These malformations can predispose individuals to dental disease, which can in turn affect …
These malformations can predispose individuals to dental disease, which can in turn affect …
Identification of enamel knot gene signature within the developing mouse molar
EW Winchester, J Cotney - bioRxiv, 2021 - biorxiv.org
In most mammals, the primary teeth develop in utero and the cells capable of contributing to
hard surface regeneration are lost before tooth eruption. These cells differentiate through a …
hard surface regeneration are lost before tooth eruption. These cells differentiate through a …
Towards genome wide RNA imaging in single cells
C Xia - 2021 - search.proquest.com
Quantitative and spatial analysis of full transcriptomes in single cells is crucial for our
understanding of the interplay between cellular and even subcellular heterogeneity and …
understanding of the interplay between cellular and even subcellular heterogeneity and …