Spatial transcriptomics is a rapidly growing field that promises to comprehensively
characterize tissue organization and architecture at the single-cell or subcellular resolution …

Background Tumors can evolve and adapt to therapeutic pressure by acquiring genetic and
epigenetic alterations that may be transient or stable. A precise understanding of how such …

RNA splicing is an important driver of heterogeneity in single cells through the expression of
alternative transcripts and as a determinant of transcriptional kinetics. However, the intrinsic …

Human odontogenic aberrations such as abnormal tooth number and delayed tooth eruption
can occur as a symptom of rare syndromes or, more commonly, as nonsyndromic …

Human genital infections are one of the most concerning issues worldwide and can be
categorized into sexually transmitted, urinary tract and vaginal infections. These infections, if …

Dental malformations range from rare syndromes to common nonsyndromic phenotypes.
These malformations can predispose individuals to dental disease, which can in turn affect …

In most mammals, the primary teeth develop in utero and the cells capable of contributing to
hard surface regeneration are lost before tooth eruption. These cells differentiate through a …

Quantitative and spatial analysis of full transcriptomes in single cells is crucial for our
understanding of the interplay between cellular and even subcellular heterogeneity and …