This article summarizes anatomical, neurophysiological, pharmacological, and brain
imaging studies in humans and animals that have provided insights into the neural circuitry …

The detrusor smooth muscle is the main muscle component of the urinary bladder wall. Its
ability to contract over a large length interval and to relax determines the bladder function …

OBJECTIVES: The functions of the lower urinary tract (LUT) to store and periodically release
urine are dependent on neural circuits in the brain and spinal cord. This paper reviews the …

Micturition in cats and rats with an intact neuraxis is dependent upon a spinobulbospinal
reflex activated by Aδ bladder afferents. This report describes changes in micturition reflexes …

Urethral obstruction produces increased voiding frequency (0.7+/-0.06 to 1.1+/-0.08 h-1) and
hypertrophy of the urinary bladder (89+/-1.7 to 708+/-40 mg) with profound increments in the …

The urinary bladder and its outlet, the urethra, serve 2 main functions: the storage of urine
without leakage, and the periodic release of urine. These 2 functions are dependent on …

Spinal cord injury and cyclophosphamide-induced cystitis dramatically alter lower urinary
tract function and produce neurochemical, electrophysiological, and anatomical changes …

Aims In this review we try to shed light on the following questions: How frequently are
symptoms of overactive bladder (OAB) and is detrusor overactivity (DO) present in patients …

Purpose: To identify and quantitate alpha1-adrenergic receptor (alpha1 AR) subtype
expression in human detrusor. Materials and Methods: Initial studies to determine alpha1 …

The case is compelling for the involvement of nerve growth factor (NGF) in the pathogenesis
of lower urinary tract disease, especially in conditions with altered neural function …