The field of cancer immunotherapy has shown significant growth, and researchers are now
focusing on effective strategies to enhance and prolong local immunomodulation. Injectable …

Toll-like receptors (TLR) play a dual regulatory role in the tumor microenvironment (TME).
TLR agonists (TLRa) elicit both innate and adaptive immune responses to achieve anti …

In recent years, engineering biocompatible HDL nanodiscs has garnered a great interest
with wide applications for for both drug delivery and structural biology. In this review, we …

Traditional approaches to cancer vaccines elicit weak CD8+ T cell responses and have
largely failed to meet clinical expectations. This is in part due to inefficient antigen cross …

Cancer vaccine efficacy is limited by the immunosuppressive nature of the tumor
microenvironment created by inflammation, immune inhibitory factors, and regulatory T cells …

A synergistic combination of treatment with immunogenic cell death (ICD) inducers and
immunoadjuvants may be a practical way to boost the anticancer response and successfully …

Neoantigen-based cancer vaccines have emerged as a promising immunotherapeutic
approach to treat cancer. Nevertheless, the high degree of heterogeneity in tumors poses a …

Nowadays, there has been an increasing utilization of nanomedicines for disease treatment.
Nanodiscs (NDs) have emerged as a novel platform technology that garners significant …

Preclinical, clinical and epidemiologic studies have established the potent anticancer and
radiosensitisation effects of HMG-CoA reductase inhibitors (statins). However, the low …

Obesity is defined as chronic, low-grade inflammation within specific tissues. Given the
escalating prevalence of obesity among individuals of all ages, obesity has reached …