Canonical fibroblast growth factors in viral infection

G Lottini, E Plicanti, M Lai, P Quaranta… - Reviews in Medical …, 2023 - Wiley Online Library
Fibroblast growth factors (FGFs) are a family of proteins that play a crucial role in the
development and maintenance of various tissues in the body. There are three function‐al …

FGF signalling facilitates cervical cancer progression

HTNA Mahmood, E Tomas Bort, AJ Walker… - The FEBS …, 2022 - Wiley Online Library
Cervical cancer is one of the most frequently diagnosed cancers in women worldwide. While
cervical cancer is caused by human papillomavirus (HPV), not all females infected with HPV …

Regulation of the human papillomavirus lifecyle through post-translational modifications of the viral E2 protein

L Jose, T Gilson, EJ Androphy, M DeSmet - Pathogens, 2021 - mdpi.com
The human papillomavirus (HPV) is a DNA tumor virus that infects cutaneous and mucosal
epithelia where high-risk (HR) HPV infections lead to cervical, oropharyngeal, and …

Inferring Virus-Host relationship between HPV and its host Homo sapiens using protein interaction network

QA Farooq, Z Shaukat, T Zhou, S Aiman, W Gong… - Scientific Reports, 2020 - nature.com
Human papilloma virus (HPV) is a serious threat to human life globally with over 100
genotypes including cancer causing high risk HPVs. Study on protein interaction maps of …

Phosphorylation of a conserved tyrosine in the papillomavirus E2 protein regulates Brd4 binding and viral replication

M DeSmet, L Jose, N Isaq, EJ Androphy - Journal of Virology, 2019 - Am Soc Microbiol
The papillomavirus (PV) E2 protein coordinates viral transcription and genome replication.
Following a strategy to identify amino acids in E2 that are posttranslationally modified, we …

Pyk2 regulates human papillomavirus replication by tyrosine phosphorylation of the E2 protein

L Jose, M DeSmet, EJ Androphy - Journal of Virology, 2020 - Am Soc Microbiol
The human papillomavirus (HPV) E2 protein is a key regulator of viral transcription and
replication. In this study, we demonstrate that the nonreceptor tyrosine kinase Pyk2 …

Human papillomavirus (HPV) viral proteins substitute for the impact of somatic mutations by affecting cancer-related genes: Meta-analysis and perspectives

Z Shang, VL Kouznetsova… - Journal of Infectiology …, 2020 - infectiologyjournal.com
Purpose: Although a strong association between human papillomavirus (HPV) and a variety
of cancers has long been established, infection by HPV alone has been shown to be …

Human papillomavirus 31 tyrosine 102 regulates interaction with E2 binding partners and episomal maintenance

T Gilson, S Culleton, F Xie, M DeSmet… - Journal of …, 2020 - Am Soc Microbiol
Several serine and threonine residues of the papillomavirus early E2 protein have been
found to be phosphorylated. In contrast, only one E2 tyrosine phosphorylation site in BPV-1 …

[图书][B] The Eukaryotic SMC5/6 Complex Represses the Replicative Program of High-Risk Human Papillomavirus

RT Gibson - 2020 - search.proquest.com
Human papillomaviruses (HPVs) are non-enveloped, circular double-stranded DNA viruses
that infect basal keratinocytes of stratified squamous epithelia. High-risk HPV (HR-HPV) …

Emerging role of FGF receptors in papillomavirus replication

L Jose, EJ Androphy, M DeSmet - Future Virology, 2018 - Taylor & Francis
Human papillomaviruses (HPV) are small DNA tumor viruses infecting cervix, mouth and
throat tissues leading to cervical, oropharyngeal and anogenital cancers [1]. The HPV being …