Hereditary cone disorders (CDs) are characterized by defects of the cone photoreceptors or
retinal pigment epithelium underlying the macula, and include achromatopsia (ACHM), cone …

In this review, we summarize studies investigating the types and distribution of voltage-and
calcium-gated ion channels in the different classes of retinal neurons: rods, cones …

Cone photoreceptor disorders form a clinical spectrum of diseases that include progressive
cone dystrophy (CD) and complete and incomplete achromatopsia (ACHM). The underlying …

Achromatopsia (ACHM) is an autosomal-recessive retinal dystrophy characterized by color
blindness, photophobia, nystagmus, and severely reduced visual acuity. Its prevalence has …

There is growing evidence that Müller glia cells (MGCs) might act as regenerative elements
in injured retinas of fishes and amniotes. However, their differentiation potential in humans is …

Myopia is the most common cause of visual impairment worldwide. Genetic and
environmental factors contribute to the development of myopia. Studies on the molecular …

OBJECTIVE: To evaluate the clinical course, genetic etiology, and visual prognosis in
patients with cone dystrophy (CD) and cone–rod dystrophy (CRD). DESIGN: Clinic-based …

Vision begins in the retina, whose intricate neural circuits extract salient features of the
environment from the light entering our eyes. Neurodegenerative diseases of the retina (eg …

With the rapid expansion of methods encompassed by the term gene therapy, new trials
exploring the safety and efficacy of these methods are initiated more frequently. As a result …

Abstract Retinitis pigmentosa 1–like 1 (RP1L1) is a component of the photoreceptor cilium.
Pathogenic variants in RP1L1 lead to photoreceptor disease, suggesting an important role …