Glucocorticoid hormones were discovered to have use as potent anti-inflammatory and
immunosuppressive therapeutics in the 1940s and their continued use and development …

Glucocorticoids (GCs) are steroids secreted by the adrenal cortex under the hypothalamic-
pituitary-adrenal axis control, one of the major neuro-endocrine systems of the organism …

摘要糖皮质激素诱导的高血糖是一个常见的医疗问题, 它使患者频繁至急诊室就诊,
并延长入院及住院时间, 除此之外还有众所周知的高血糖导致死亡率增加的问题. 然而 …

Therapeutic glucocorticoids have been widely used in rheumatic diseases since they
became available over 60 years ago. Despite the advent of more specific biologic therapies …

Many pathological states characterized by muscle atrophy (eg, sepsis, cachexia, starvation,
metabolic acidosis and severe insulinopenia) are associated with an increase in circulating …

Osteoporosis associated with long-term glucocorticoid therapy remains a common and
serious bone disease. Additionally, in recent years it has become clear that more subtle …

Vitamin D (VD) is essential for bone homeostasis, but it is also involved in pleiotropic effects
on various organs and tissues. In adults, VD deficiency can cause or exacerbate …

Mammalian skeletal muscles are composed of a variety of highly specialized fibers whose
selective recruitment allows muscles to fulfill their diverse functional tasks. In addition …

At pharmacological concentrations, glucocorticoids (GCs) display potent anti‐inflammatory
effects, and are therefore frequently prescribed by physicians to treat a wide variety of …

▪ Abstract This review is divided into two parts, the first dealing with the cell and molecular
biology of muscle in terms of growth and wasting and the second being an account of …