Multi-functional chitosan-based nanoparticles for drug delivery: Recent advanced insight into cancer therapy
B Tian, S Hua, J Liu - Carbohydrate Polymers, 2023 - Elsevier
Cancer therapy continues to be a major global concern, with conventional treatments
suffering from low efficacy, untargeted drug delivery, and severe side effects. Recent …
suffering from low efficacy, untargeted drug delivery, and severe side effects. Recent …
Amelioration of cancer employing chitosan, its derivatives, and chitosan-based nanoparticles: recent updates
The limitations associated with the conventional treatment of cancer have necessitated the
design and development of novel drug delivery systems based mainly on nanotechnology …
design and development of novel drug delivery systems based mainly on nanotechnology …
Exploring the current landscape of chitosan-based hybrid nanoplatforms as cancer theragnostic
In the last decade, investigators have put significant efforts to develop several diagnostic
and therapeutic strategies against cancer. Many novel nanoplatforms, including lipidic …
and therapeutic strategies against cancer. Many novel nanoplatforms, including lipidic …
Chitosan-Coated PLGA Nanoparticles Loaded with Peganum harmala Alkaloids with Promising Antibacterial and Wound Healing Activities
Wound healing is a major healthcare concern, and complicated wounds may lead to severe
outcomes such as septicemia and amputations. To date, management choices are limited …
outcomes such as septicemia and amputations. To date, management choices are limited …
Investigating the bone regeneration activity of PVA nanofibers scaffolds loaded with simvastatin/chitosan nanoparticles in an induced bone defect rabbit model
This study aims at preparing electrospun PVA NFs incorporating simvastatin/chitosan
nanoparticles (SIM CS NPs) as a controlled drug eluting scaffold for bone regeneration …
nanoparticles (SIM CS NPs) as a controlled drug eluting scaffold for bone regeneration …
Formulation of simvastatin chitosan nanoparticles for controlled delivery in bone regeneration: Optimization using Box-Behnken design, stability and in vivo study
This study aims to formulate and optimize simvastatin loaded chitosan-tripolyphosphate
nanoparticles (SIM CS-TPP NPs) using ionic gelation method to provide a local delivery …
nanoparticles (SIM CS-TPP NPs) using ionic gelation method to provide a local delivery …
Effects of chitosan and oligochitosans on the phosphatidylinositol 3-kinase-AKT pathway in cancer therapy
E Amirani, J Hallajzadeh, Z Asemi… - International journal of …, 2020 - Elsevier
Abstract Phosphatidylinositol 3-kinase (PI3K)-AKT pathway is one of the most important
kinase signaling networks in the context of cancer development and treatment. Aberrant …
kinase signaling networks in the context of cancer development and treatment. Aberrant …
Chitosan nanomedicine in cancer therapy: targeted delivery and cellular uptake
Nanomedicine has gained much attention for the management and treatment of cancers due
to the distinctive physicochemical properties of the drug‐loaded particles. Chitosan's …
to the distinctive physicochemical properties of the drug‐loaded particles. Chitosan's …
Nanomedicine to overcome multidrug resistance mechanisms in colon and pancreatic cancer: recent progress
Simple Summary The cellular mechanisms of drug resistance prevent the correct efficacy of
the therapies used in various types of cancer and nanotechnology has been postulated as a …
the therapies used in various types of cancer and nanotechnology has been postulated as a …
[HTML][HTML] Mast cell-T cell axis alters development of colitis-dependent and colitis-independent colorectal tumours: potential for therapeutically targeting via mast cell …
Background Colorectal cancer (CRC) has a high mortality rate and can develop in either
colitis-dependent (colitis-associated (CA)-CRC) or colitis-independent (sporadic (s) CRC) …
colitis-dependent (colitis-associated (CA)-CRC) or colitis-independent (sporadic (s) CRC) …