Tumour fatty acid metabolism in the context of therapy resistance and obesity
AJ Hoy, SR Nagarajan, LM Butler - Nature Reviews Cancer, 2021 - nature.com
Fatty acid metabolism is known to support tumorigenesis and disease progression as well
as treatment resistance through enhanced lipid synthesis, storage and catabolism. More …
as treatment resistance through enhanced lipid synthesis, storage and catabolism. More …
[HTML][HTML] Biophysics in cancer: The relevance of drug-membrane interaction studies
AC Alves, D Ribeiro, C Nunes, S Reis - Biochimica et Biophysica Acta (BBA …, 2016 - Elsevier
Lipidomics has been proving that membrane lipids play a crucial role in several cell
functions and are involved in several pathologies, including cancer. In fact, beyond a …
functions and are involved in several pathologies, including cancer. In fact, beyond a …
[HTML][HTML] Prognosis and dissection of immunosuppressive microenvironment in breast cancer based on fatty acid metabolism-related signature
Y Tang, W Tian, J Xie, Y Zou, Z Wang, N Li… - Frontiers in …, 2022 - frontiersin.org
Fatty acid metabolism has been deciphered to augment tumorigenesis and disease
progression in addition to therapy resistance via strengthened lipid synthesis, storage, and …
progression in addition to therapy resistance via strengthened lipid synthesis, storage, and …
[HTML][HTML] Drug uptake-based chemoresistance in breast cancer treatment
H Muley, R Fado, R Rodriguez-Rodriguez… - Biochemical …, 2020 - Elsevier
Breast cancer is the most prevalent type of tumor and the second leading cause of death
due to cancer among women. Although screening methods, diagnosis and therapeutic …
due to cancer among women. Although screening methods, diagnosis and therapeutic …
Biophysics of cell membrane lipids in cancer drug resistance: Implications for drug transport and drug delivery with nanoparticles
C Peetla, S Vijayaraghavalu, V Labhasetwar - Advanced drug delivery …, 2013 - Elsevier
In this review, we focus on the biophysics of cell membrane lipids, particularly when cancers
develop acquired drug resistance, and how biophysical changes in resistant cell membrane …
develop acquired drug resistance, and how biophysical changes in resistant cell membrane …
Understanding and targeting resistance mechanisms in cancer
ZN Lei, Q Tian, QX Teng, JND Wurpel, L Zeng… - MedComm, 2023 - Wiley Online Library
Resistance to cancer therapies has been a commonly observed phenomenon in clinical
practice, which is one of the major causes of treatment failure and poor patient survival. The …
practice, which is one of the major causes of treatment failure and poor patient survival. The …
[HTML][HTML] Mimicking the mammalian plasma membrane: An overview of lipid membrane models for biophysical studies
A Luchini, G Vitiello - Biomimetics, 2020 - mdpi.com
Cell membranes are very complex biological systems including a large variety of lipids and
proteins. Therefore, they are difficult to extract and directly investigate with biophysical …
proteins. Therefore, they are difficult to extract and directly investigate with biophysical …
Single-cell diagnosis of cancer drug resistance through the differential endocytosis of nanoparticles between drug-resistant and drug-sensitive cancer cells
L Liu, Q Zhang, C Wang, H Guo, V Mukwaya, R Chen… - ACS …, 2023 - ACS Publications
Single-cell diagnosis of cancer drug resistance is highly relevant for cancer treatment, as it
can be used to identify the subpopulations of drug-resistant cancer cells, reveal the …
can be used to identify the subpopulations of drug-resistant cancer cells, reveal the …
Nanoparticles: cellular uptake and cytotoxicity
IM Adjei, B Sharma, V Labhasetwar - Nanomaterial: impacts on cell …, 2014 - Springer
Understanding the interactions of nanoparticles (NPs) with cells and how these interactions
influence their cellular uptake is essential to exploring the biomedical applications of NPs …
influence their cellular uptake is essential to exploring the biomedical applications of NPs …
[HTML][HTML] Recent progressive use of atomic force microscopy in biomedical applications
U Maver, T Velnar, M Gaberšček, O Planinšek… - TrAC Trends in …, 2016 - Elsevier
In recent years, a great deal of interest has been focused on the development of novel
atomic force microscopy (AFM)-based methods. From first being an unstable method, AFM …
atomic force microscopy (AFM)-based methods. From first being an unstable method, AFM …