Mechanisms of phosphate transport

M Levi, E Gratton, IC Forster, N Hernando… - Nature Reviews …, 2019 - nature.com
Over the past 25 years, successive cloning of SLC34A1, SLC34A2 and SLC34A3, which
encode the sodium-dependent inorganic phosphate (Pi) cotransport proteins 2a–2c, has …

Phosphate transport in epithelial and nonepithelial tissue

N Hernando, K Gagnon, E Lederer - Physiological reviews, 2021 - journals.physiology.org
Phosphate is an essential nutrient for life and is a critical component of bone formation, a
major signaling molecule, and structural component of cell walls. Phosphate is also a …

Proteomic and transcriptomic profiling reveal different aspects of aging in the kidney

Y Takemon, JM Chick, I Gerdes Gyuricza, DA Skelly… - elife, 2021 - elifesciences.org
Little is known about the molecular changes that take place in the kidney during the aging
process. In order to better understand these changes, we measured mRNA and protein …

Phosphate transporters and their function

J Biber, N Hernando, I Forster - Annual review of physiology, 2013 - annualreviews.org
Plasma phosphate concentration is maintained within a relatively narrow range by control of
renal reabsorption of filtered inorganic phosphate (Pi). Pi reabsorption is a transcellular …

Advances in fluorescence microscopy techniques to study kidney function

S Ranjit, L Lanzanò, AE Libby, E Gratton… - Nature Reviews …, 2021 - nature.com
Fluorescence microscopy, in particular immunofluorescence microscopy, has been used
extensively for the assessment of kidney function and pathology for both research and …

Linear combination properties of the phasor space in fluorescence imaging

B Torrado, L Malacrida, S Ranjit - Sensors, 2022 - mdpi.com
The phasor approach to fluorescence lifetime imaging, and more recently hyperspectral
fluorescence imaging, has increased the use of these techniques, and improved the ease …

Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors

JA Ardura, PA Friedman, PA Insel - Pharmacological reviews, 2011 - Elsevier
Many G protein-coupled receptors (GPCR) exert patterns of cell-specific signaling and
function. Mounting evidence now supports the view that cytoplasmic adapter proteins …

[HTML][HTML] Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis

RA Fenton, SB Poulsen, S de la Mora Chavez… - Kidney international, 2017 - Elsevier
The sodium/proton exchanger isoform 3 (NHE3) is expressed in the intestine and the kidney,
where it facilitates sodium (re) absorption and proton secretion. The importance of NHE3 in …

Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3

RA Fenton, SB Poulsen… - American Journal …, 2015 - journals.physiology.org
Caffeine is one of the most widely consumed behavioral substances. We have previously
shown that caffeine-and theophylline-induced inhibition of renal reabsorption causes …

Chromatin nanoscale compaction in live cells visualized by acceptor‐to‐donor ratio corrected Förster resonance energy transfer between DNA dyes

S Pelicci, A Diaspro, L Lanzanò - Journal of biophotonics, 2019 - Wiley Online Library
Abstract@ Chromatin nanoscale architecture in live cells can be studied by Förster
resonance energy transfer (FRET) between fluorescently labeled chromatin components …