Tendon and ligament healing and current approaches to tendon and ligament regeneration
NL Leong, JL Kator, TL Clemens… - Journal of …, 2020 - Wiley Online Library
Ligament and tendon injuries are common problems in orthopedics. There is a need for
treatments that can expedite nonoperative healing or improve the efficacy of surgical repair …
treatments that can expedite nonoperative healing or improve the efficacy of surgical repair …
Practical considerations for translating mesenchymal stromal cell-derived extracellular vesicles from bench to bed
Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) have shown
potential for the treatment of tendon and ligament injuries. This approach can eliminate the …
potential for the treatment of tendon and ligament injuries. This approach can eliminate the …
Treatment of lateral epicondylosis by using allogeneic adipose-derived mesenchymal stem cells: a pilot study
Mesenchymal stem cell therapy is a novel regenerative approach for treating tendinopathy.
Here, we evaluated the safety and efficacy of allogeneic adipose-derived mesenchymal …
Here, we evaluated the safety and efficacy of allogeneic adipose-derived mesenchymal …
Human mesenchymal stem cells modulate inflammatory cytokines after spinal cord injury in rat
L Machová Urdzíková, J Růžička, M LaBagnara… - International journal of …, 2014 - mdpi.com
Transplantation of mesenchymal stem cells (MSC) improves functional recovery in
experimental models of spinal cord injury (SCI); however, the mechanisms underlying this …
experimental models of spinal cord injury (SCI); however, the mechanisms underlying this …
[HTML][HTML] Rescue plan for Achilles: Therapeutics steering the fate and functions of stem cells in tendon wound healing
M Schneider, P Angele, TAH Järvinen… - Advanced drug delivery …, 2018 - Elsevier
Due to the increasing age of our society and a rise in engagement of young people in
extreme and/or competitive sports, both tendinopathies and tendon ruptures present a …
extreme and/or competitive sports, both tendinopathies and tendon ruptures present a …
Mitochondrial transfer from bone mesenchymal stem cells protects against tendinopathy both in vitro and in vivo
B Wei, M Ji, Y Lin, S Wang, Y Liu, R Geng, X Hu… - Stem Cell Research & …, 2023 - Springer
Background Although mesenchymal stem cells (MSCs) have been effective in tendinopathy,
the mechanisms by which MSCs promote tendon healing have not been fully elucidated. In …
the mechanisms by which MSCs promote tendon healing have not been fully elucidated. In …
Electrospun PLGA fiber diameter and alignment of tendon biomimetic fleece potentiate tenogenic differentiation and immunomodulatory function of amniotic epithelial …
M El Khatib, A Mauro, M Di Mattia, R Wyrwa… - Cells, 2020 - mdpi.com
Injured tendons are challenging in their regeneration; thus, tissue engineering represents a
promising solution. This research tests the hypothesis that the response of amniotic …
promising solution. This research tests the hypothesis that the response of amniotic …
Cerium oxide nanoparticles-carrying human umbilical cord mesenchymal stem cells counteract oxidative damage and facilitate tendon regeneration
X Ren, H Zhuang, Y Zhang, P Zhou - Journal of Nanobiotechnology, 2023 - Springer
Background Tendon injuries have a high incidence and limited treatment options. Stem cell
transplantation is essential for several medical conditions like tendon injuries. However …
transplantation is essential for several medical conditions like tendon injuries. However …
The roles and therapeutic potentialof mesenchymal stem/stromal cells and their extracellular vesicles in tendinopathies
D Quintero, C Perucca Orfei, LD Kaplan… - … in Bioengineering and …, 2023 - frontiersin.org
Tendinopathies encompass a highly prevalent, multi-faceted spectrum of disorders,
characterized by activity-related pain, compromised function, and propensity for an extended …
characterized by activity-related pain, compromised function, and propensity for an extended …
SM04755, a small‐molecule inhibitor of the Wnt pathway, as a potential topical treatment for tendinopathy
V Deshmukh, T Seo, AL O'Green… - Journal of …, 2021 - Wiley Online Library
The Wnt pathway is upregulated in tendinopathy, affecting inflammation and tenocyte
differentiation. Given its potential role in tendinopathy, this signaling pathway may be a …
differentiation. Given its potential role in tendinopathy, this signaling pathway may be a …