Visible-to-NIR-light activated release: from small molecules to nanomaterials
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
Development of triggerable, trackable, and targetable carbon monoxide releasing molecules
LS Lazarus, AD Benninghoff… - Accounts of chemical …, 2020 - ACS Publications
Conspectus Carbon monoxide (CO) is a gaseous signaling molecule produced in humans
via the breakdown of heme in an O2-dependent reaction catalyzed by heme oxygenase …
via the breakdown of heme in an O2-dependent reaction catalyzed by heme oxygenase …
External stimuli-responsive gasotransmitter prodrugs: Chemistry and spatiotemporal release
Gasotransmitters like nitric oxide, carbon monoxide, and hydrogen sulfide with unique
pleiotropic pharmacological effects in mammals are an emerging therapeutic modality for …
pleiotropic pharmacological effects in mammals are an emerging therapeutic modality for …
Medical gas therapy for tissue, organ, and CNS protection: a systematic review of effects, mechanisms, and challenges
RD Zafonte, L Wang, CA Arbelaez… - Advanced …, 2022 - Wiley Online Library
Gaseous molecules have been increasingly explored for therapeutic development. Here,
following an analytical background introduction, a systematic review of medical gas …
following an analytical background introduction, a systematic review of medical gas …
[HTML][HTML] Nature's marvels endowed in gaseous molecules I: carbon monoxide and its physiological and therapeutic roles
Nature has endowed gaseous molecules such as O 2, CO 2, CO, NO, H 2 S, and N 2 with
critical and diverse roles in sustaining life, from supplying energy needed to power life and …
critical and diverse roles in sustaining life, from supplying energy needed to power life and …
Chemical reactivities of two widely used ruthenium-based CO-releasing molecules with a range of biologically important reagents and molecules
Ruthenium-based CO-releasing molecules (CO-RMs), CORM-2 and CORM-3, have been
widely used as surrogates of CO for studying its biological effects in vitro and in vivo with …
widely used as surrogates of CO for studying its biological effects in vitro and in vivo with …
Metal-free carbon monoxide-releasing micelles undergo tandem photochemical reactions for cutaneous wound healing
J Cheng, B Zheng, S Cheng, G Zhang, J Hu - Chemical science, 2020 - pubs.rsc.org
Carbon monoxide (CO) has shown broad biomedical applications. The site-specific delivery
and controlled release of CO is of crucial importance to achieve maximum therapeutic …
and controlled release of CO is of crucial importance to achieve maximum therapeutic …
Visible-light-activated carbon monoxide release from porphyrin–flavonol hybrids
We report on porphyrin–flavonol hybrids consisting of a porphyrin antenna and four
covalently bound 3-hydroxyflavone (flavonol) groups, which act as highly efficient …
covalently bound 3-hydroxyflavone (flavonol) groups, which act as highly efficient …
Light-assisted and remote delivery of carbon monoxide to malignant cells and tissues: Photochemotherapy in the spotlight
MN Pinto, PK Mascharak - Journal of Photochemistry and Photobiology C …, 2020 - Elsevier
The recent discovery of the salutary effects of carbon monoxide (CO) in chronic obstructive
pulmonary disease (COPD), ischemic perfusion damage, graft implantation, as well as its …
pulmonary disease (COPD), ischemic perfusion damage, graft implantation, as well as its …
Fluorescent small molecule donors
Small molecule donors (SMDs) play subtle roles in the signaling mechanism and disease
treatments. While many excellent SMDs have been developed, dosage control, targeted …
treatments. While many excellent SMDs have been developed, dosage control, targeted …