The use of drug powders containing micronized drug particles has been increasing in
several pharmaceutical dosage forms to overcome the dissolution and bioavailability …

Optimized physical properties (eg, bulk, surface/interfacial, and mechanical properties) of
active pharmaceutical ingredients (APIs) are key to the successful integration of drug …

The purpose of the study is to enhance dissolution of spironolactone as a model
hydrophobic drug through application of liquisolid technology. Spironolactone is prepared …

Liquisolid systems were originally designed to enhance dissolution of hydrophobic drugs.
Recently, the same technique was explored to control drug release via hydrophobic carriers …

Purpose In this study, coamorphous form of atorvastatin calcium (ATC) with two drugs, ie,
carvedilol (CVD) and glibenclamide (GLN) in 1: 1 stoichiometry, were prepared from solvent …

A new ionic liquid solvent was prepared from choline as a cation and tryptophan as the
anion. The produced ionic liquid was characterized by NMR, UV and HPLC. The obtained …

The negligible volatility and high tunable nature of ionic liquids (ILs) have been the main
drivers of their investigation in a wide diversity of fields, among which is their application in …

Novel LNCs (lipid nanocrystals) were developed with an aim to improve the solubility,
stability and targeting efficiency of the model drug glibenclamide (GLB). PEG 20000, Tween …

Objective: The aim of this work was to investigate the potential of controlled precipitation of
flurbiprofen on solid surface, in the presence or absence of hydrophilic polymers, as a tool …

Self-nanoemulsifying drug delivery systems (SNEDDS) have been widely applied to
improve the dissolution and bioavailability of hydrophobic medications like glibenclamide …