The main function of the lungs is oxygen transport from the atmosphere into the blood
circulation, while it is necessary to keep the pulmonary tissue relatively free of pathogens …

Introduction: Bronchiectasis is a chronic endobronchial suppurative disease characterized
by irreversibly dilated bronchi damaged by repeated polymicrobial infections and …

Abstract Ethnopharmacological relevance Radix Bupleuri (Bupleurum chinense DC.) is a
traditional Chinese medicine that has the effect of soothing the liver and relieving …

The respiratory system is constantly exposed to pathogens which enter the lungs by
inhalation or via blood stream. Lipopolysaccharide (LPS), also named endotoxin, can reach …

Alveolar epithelial cells (AECs) function as a vital defense barrier avoiding the invasion of
exogenous agents and preserving the functional and structural integrity of lung tissues …

Abstract Background In December 2016, WHO released a report stating that in 2015 there
were 383,000 deaths caused by asthma and 235 million people suffering from asthma. As …

Alveolar epithelial type II (ATII) cells and their proper function are essential for maintaining
lung integrity and homeostasis. However, they can be damaged by lipopolysaccharide …

The epithelial barrier of the lung is destroyed during acute lung injury (ALI)/acute respiratory
distress syndrome (ARDS) due to the apoptosis of alveolar epithelial cells (AECs) …

Acute lung injury (ALI) is a common, costly and potentially lethal disease with characteristics
of alveolar‑capillary membrane disruption, pulmonary edema and impaired gas exchange …

Various biomolecules induce neutrophil extracellular trap (NET) formation or NETosis.
However, the effect of fatty acids on NETosis has not been clearly established. In this study …