Estrogens have historically been associated with female reproduction, but work over the last
two decades established that estrogens and their main nuclear receptors (ESR1 and ESR2) …

Estrogen, hormonal replacement therapy and cardiovascular di... : Current Opinion in
Nephrology and Hypertension Estrogen, hormonal replacement therapy and cardiovascular …

The extracellular matrix (ECM) is a complex entity containing a large portfolio of structural
proteins, signaling molecules, and proteases. Changes in the overall integrity and …

Heart disease has always been one of the important diseases that endanger health and
cause death. Therefore, it is particularly important to understand left atrium reconstruction …

Cardiac hypertrophy is an adaptive response to abnormal physiological and pathological
stimuli, which can be classified into concentric and eccentric hypertrophy, induced by …

Hormones have a vital duty in the conservation of physiological cardiovascular function
during pregnancy. Alterations in oestrogen, progesterone and prolactin levels are …

The mammalian heart during its development and in response to physiological or
pathological stimuli undergoes hypertrophic enlargement, a consequence of an increase in …

Our previous studies demonstrate that 17β-estradiol limits chronic volume overload-induced
hypertrophy and improves heart function in ovariectomized rats. One possible …

During Pregnancy, heart develops physiological left ventricular hypertrophy as a result of the
natural volume overload. Previously we have characterized the molecular and functional …

Although well documented drug therapies are available for the management of ventricular
hypertrophy (VH) and heart failure (HF), most patients nonetheless experience a downhill …