[HTML][HTML] Autophagy during viral infection—a double-edged sword

Y Choi, JW Bowman, JU Jung - Nature Reviews Microbiology, 2018 - nature.com
Autophagy is a powerful tool that host cells use to defend against viral infection. Double-
membrane vesicles, termed autophagosomes, deliver trapped viral cargo to the lysosome …

The role of autophagy in viral infections

T Chen, S Tu, L Ding, M Jin, H Chen, H Zhou - Journal of biomedical …, 2023 - Springer
Autophagy is an evolutionarily conserved catabolic cellular process that exerts antiviral
functions during a viral invasion. However, co-evolution and co-adaptation between viruses …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

[HTML][HTML] Viruses and the autophagy pathway

WT Jackson - Virology, 2015 - Elsevier
Studies of the cellular autophagy pathway have exploded over the past twenty years. Now
appreciated as a constitutive degradative mechanism that promotes cellular homeostasis …

BHRF1, a BCL2 viral homolog, disturbs mitochondrial dynamics and stimulates mitophagy to dampen type I IFN induction

G Vilmen, D Glon, G Siracusano, M Lussignol, Z Shao… - Autophagy, 2021 - Taylor & Francis
Mitochondria respond to many cellular functions and act as central hubs in innate immunity
against viruses. This response is notably due to their role in the activation of interferon (IFN) …

The autophagy machinery interacts with EBV capsids during viral envelope release

M Pena-Francesch, LD Vanoaica… - Proceedings of the …, 2023 - National Acad Sciences
Autophagy serves as a defense mechanism against intracellular pathogens, but several
microorganisms exploit it for their own benefit. Accordingly, certain herpesviruses include …

Autophagy and mammalian viruses: roles in immune response, viral replication, and beyond

P Paul, C Münz - Advances in virus research, 2016 - Elsevier
Autophagy is an important cellular catabolic process conserved from yeast to man. Double-
membrane vesicles deliver their cargo to the lysosome for degradation. Hence, autophagy is …

[HTML][HTML] Epstein-Barr virus lytic reactivation regulation and its pathogenic role in carcinogenesis

H Li, S Liu, J Hu, X Luo, N Li, AM Bode… - International journal of …, 2016 - ncbi.nlm.nih.gov
Epstein-Barr virus (EBV) has been associated with several types of human cancers. In the
host, EBV can establish two alternative modes of life cycle, known as latent or lytic and the …

New look of EBV LMP1 signaling landscape

L Wang, S Ning - Cancers, 2021 - mdpi.com
Simple Summary Epstein-Barr Virus (EBV) infection is associated with various lymphomas
and carcinomas as well as other diseases in humans. The transmembrane protein LMP1 …

Autophagy, EVs, and infections: a perfect question for a perfect time

ML Pleet, H Branscome, C DeMarino… - Frontiers in cellular …, 2018 - frontiersin.org
Autophagy, a highly conserved process, serves to maintain cellular homeostasis in
response to an extensive variety of internal and external stimuli. The classic, or canonical …