Since its cloning in 1994, leptin has emerged in the literature as a pleiotropic hormone
whose actions extend from immune system homeostasis to reproduction and angiogenesis …

Acute lung injury is a severe complication to acute pancreatitis and a significant health
problem associated with a considerable mortality. Underlying mechanisms are complex and …

Adiponectin is an adipocyte-derived collectin that acts on a wide range of tissues including
liver, brain, heart, and vascular endothelium. To date, little is known about the actions of …

The incidence of acute pancreatitis, an inflammation of the pancreas, is increasing
worldwide. Pancreatic injury is mild in 80%-90% of patients who recover without …

Glycyrrhizic acid (GA), an active ingredient in licorice, has multiple pharmacological
activities. However, the effects of GA on sepsis-induced acute lung injury (ALI) have not …

Adipose tissue products or adipokines play a major role in chronic endocrine and metabolic
disorders; however, little is known about critical conditions. In this article, the experimental …

Growing scientific evidence has unveiled increased incidences of obesity in domestic
animals and its influence on a plethora of associated disorders. Leptin, an adipokine …

Background. Naringenin (Nar) is a type of flavonoid and has been shown to have anti‐
inflammatory and antioxidative properties. However, the effects of Nar on acute pancreatitis …

Obesity is clearly an independent risk factor for increased severity of acute pancreatitis (AP),
although the mechanisms underlying this association are unknown. Adipokines (including …

Acute pancreatitis is a severe inflammatory disorder with limited treatment options. Improved
understanding of disease mechanisms has led to new and potential therapies. Here we …