Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …

Small molecule based inhibitors development is a growing field in medicinal chemistry. In
recent years, different heterocyclic derivatives have been designed to counter the infections …

The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

As the carrier of genetic information, the DNA double helix interacts with many natural
ligands during the cell cycle, and is amenable to such intervention in diseases such as …

Thiophene, as a member of the group of five‐membered heterocycles containing one
heteroatom, is one of the simplest heterocyclic systems. Many synthetic strategies allow the …

Despite a significant work that has been done on thiophene, continuous efforts are still being
made by the researchers to identify novel heterocyclic compounds with potential …

Thiophene has emerged as a potent scaffold that has pulled the keen interest of the
researchers because of its considerable diversity in biological activities. The versatility of the …

Antimicrobial and chemotherapy resistance are escalating medical problem of paramount
importance. Yet, research for novel antimicrobial and anticancer agents remains lagging …

The reactivity of amidines makes them valuable as building blocks for the synthesis of
heterocyclic motifs of biological relevance, for functional materials, for organo-catalysts and …

Four series of new hybrid molecules with 7-chloroquinoline and arylamidine moieties joined
through the rigid-O-(groups I (2a-g) and II (5a-g)) or flexible-NH-CH 2-CH 2-O-(groups III (8a …