The gut–liver axis and gut microbiota in health and liver disease

CL Hsu, B Schnabl - Nature Reviews Microbiology, 2023 - nature.com
The trillions of microorganisms in the human intestine are important regulators of health, and
disruptions in the gut microbial communities can cause disease. The gut, liver and immune …

Fungal endocarditis: pathophysiology, epidemiology, clinical presentation, diagnosis, and management

GR Thompson III, JD Jenks, JW Baddley… - Clinical microbiology …, 2023 - Am Soc Microbiol
Fungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated
with high morbidity and mortality (> 70%), and presents numerous challenges during clinical …

The Interplay between Candida albicans, Vaginal Mucosa, Host Immunity and Resident Microbiota in Health and Disease: An Overview and Future Perspectives

R Gaziano, S Sabbatini, C Monari - Microorganisms, 2023 - mdpi.com
Vulvovaginal candidiasis (VVC), which is primarily caused by Candida albicans, is an
infection that affects up to 75% of all reproductive-age women worldwide. Recurrent VVC …

We need to talk about Candida tropicalis: Virulence factors and survival mechanisms

MM Dos Santos, K Ishida - Medical mycology, 2023 - academic.oup.com
Candida tropicalis is a notable species of the Candida genus representing an impressive
epidemiology in tropical regions, especially in South America and Asia, where India already …

Fungi and cancer

A Saftien, J Puschhof, E Elinav - Gut, 2023 - gut.bmj.com
The microbiome may impact cancer development, progression and treatment
responsiveness, but its fungal components remain insufficiently studied in this context. In this …

Nanobody-mediated neutralization of candidalysin prevents epithelial damage and inflammatory responses that drive vulvovaginal candidiasis pathogenesis

M Valentine, P Rudolph, A Dietschmann, A Tsavou… - MBio, 2024 - Am Soc Microbiol
Candida albicans can cause mucosal infections in humans. This includes oropharyngeal
candidiasis, which is commonly observed in human immunodeficiency virus infected …

Candidalysin: Connecting the pore forming mechanism of this virulence factor to its immunostimulatory properties

CM Russell, JA Rybak, J Miao, BM Peters… - Journal of Biological …, 2023 - ASBMB
Candida albicans is a deadly pathogen responsible for millions of mucosal and systemic
infections per year. The pathobiology of C. albicans is largely dependent on the damaging …

[HTML][HTML] “Under Pressure”–How fungi evade, exploit, and modulate cells of the innate immune system

T Lange, L Kasper, MS Gresnigt, S Brunke… - Seminars in Immunology, 2023 - Elsevier
The human immune system uses an arsenal of effector mechanisms to prevent and
counteract infections. Yet, some fungal species are extremely successful as human …

[HTML][HTML] Candida albicans Induces Oral Microbial Dysbiosis and Promotes Oral Diseases

B Kashyap, SR Padala, G Kaur, A Kullaa - Microorganisms, 2024 - mdpi.com
Candida albicans are ubiquitous fungal organisms that colonize the oral cavity of healthy
individuals without causing disease. C. albicans is an opportunistic microorganism with …

The evil companion of OSCC: Candida albicans

Z Yang, S Zhang, N Ji, J Li, Q Chen - Oral Diseases, 2024 - Wiley Online Library
Objective Microbial dysbiosis and microbiome‐induced inflammation may play a role in the
etiopathogenesis of oral squamous cell carcinoma (OSCC). Candida albicans (C. albicans) …