Carbapenemase-producing Enterobacteriaceae (CPE) are an important and increasing
threat to global health. Both clonal spread and plasmid-mediated transmission contribute to …

Carbapenem-resistant Acinetobacter baumannii (CRAB) is a perilous nosocomial pathogen
causing substantial morbidity and mortality. Current treatment options for CRAB are limited …

SKESA is a DeBruijn graph-based de-novo assembler designed for assembling reads of
microbial genomes sequenced using Illumina. Comparison with SPAdes and MegaHit …

Background The efficacy of ceftazidime-avibactam—a cephalosporin–β-lactamase inhibitor
combination with in vitro activity against Klebsiella pneumoniae carbapenemase–producing …

Summary Background Carbapenem-resistant Enterobacterales (CRE) are a global threat.
We aimed to describe the clinical and molecular characteristics of Centers for Disease …

Purpose Carbapenem resistant K. pneumoniae (CRKP) has aroused widespread attention
owing to its very limited therapeutic options, and this strain has increased rapidly in recent …

Antibiotic resistance has increased markedly in gram-negative bacteria over the last two
decades, and in many cases has been associated with increased mortality and healthcare …

Klebsiella pneumoniae carbapenemases (KPCs) were first identified in 1996 in the USA.
Since then, regional outbreaks of KPC-producing K. pneumoniae (KPC-Kp) have occurred …

Antimicrobial resistance is a normal evolutionary process for microorganisms. Antibiotics
exerted accelerated selective pressure that hasten bacterial resistance through mutation …

The comparative efficacy of ceftazidime-avibactam and meropenem-vaborbactam for
treatment of carbapenem-resistant Enterobacteriaceae (CRE) infections remains unknown …