Importance Low-dose aspirin has been widely used for primary and secondary prevention of
stroke. The balance between potential reduction of ischemic stroke events and increased …

Background & Aims Patients with early-onset colorectal cancer (eoCRC) are managed
according to guidelines that are not age-specific. A multidisciplinary international group …

Importance Aspirin is an effective and low-cost option for reducing atherosclerotic
cardiovascular disease (CVD) events and improving mortality rates among individuals with …

Background Aspirin as a primary preventative in healthy older adults did not prolong
disability-free survival in the ASPREE randomized trial. Observational studies following …

Background: Daily low-dose aspirin increases major bleeding; however, few studies have
investigated its effect on iron deficiency and anemia. Objective: To investigate the effect of …

Aims Aspirin therapy for primary prevention of cardiovascular disease (CVD) is
controversial, and guideline recommendations have changed throughout the last decades …

Background Recent guidelines do not recommend routine use of aspirin for primary
cardiovascular prevention (ppASA) and suggest avoidance of ppASA in older individuals …

Background Thoracic endovascular aortic repair (TEVAR) is a minimally invasive technique
used to treat type B aortic dissections. Left subclavian artery (LSA) reconstruction is required …

Aspirin is a recognized and affordable antiplatelet medicine. Low amounts of aspirin have
been used to prevent cardiovascular events, and it is still widely used for primary and …

Background The net benefit of aspirin cessation in older adults remains uncertain. This study
aimed to use observational data to emulate a randomized trial of aspirin cessation versus …