The innate immune response provides the first line of defense against invading pathogens,
and immune disorders cause a variety of diseases. The fruit fly Drosophila melanogaster …

Intracellular membrane traffic defines a complex network of pathways that connects many of
the membrane-bound organelles of eukaryotic cells. Although each pathway is governed by …

Rab proteins are small GTPases that act as essential regulators of vesicular trafficking. 44
subfamilies are known in humans, performing specific sets of functions at distinct subcellular …

Early endosomes consist of vacuolar sorting and tubular recycling domains that segregate
components fated for degradation in lysosomes or reuse by recycling to the plasma …

Dorsal closure is a key process during Drosophila morphogenesis that models cell sheet
movements in chordates, including neural tube closure, palate formation, and wound …

Understanding the molecular basis of wound healing and regeneration in vertebrates is one
of the main challenges in biology and medicine. This understanding will lead to medical …

The obligate intracellular protozoan Toxoplasma gondii actively invades mammalian cells
and, upon entry, forms its own membrane-bound compartment, named the parasitophorous …

The Jun‐N‐terminal Kinase pathway (JNK), known also as stress activated protein kinase
pathway (SAPK), is an eukaryotic evolutionarily conserved signaling pathway. From a …

Toxoplasma gondii and Neospora caninum, which cause the diseases toxoplasmosis and
neosporosis, respectively, are two closely related apicomplexan parasites. They have …

Kinesin heavy chain (Khc) is crucially required for axonal transport and khc mutants show
axonal swellings and paralysis. Here, we demonstrate that in Drosophila khc is equally …