Recent progress in engineering highly promising biocatalysts has increasingly involved
machine learning methods. These methods leverage existing experimental and simulation …

Covering: up to 2021 Terpenoids are physiologically active substances that are of great
importance to humans. Their physicochemical properties are modified by glycosylation, in …

Cardiotonic steroids (CTSs) are ancient and effective clinical drugs for treating heart failure.
Glycosylation of the CTS, especially at the C-3 position, is of great significance in nowadays …

Glycosyltransferases (GTs) catalyze the transfer of active monosaccharide donors to
carbohydrates to create a wide range of oligosaccharide structures. GTs display strong …

Polyphenolic compounds (such as quercetin and resveratrol) possess potential medicinal
values due to their various bioactivities, but poor water solubility hinders their health benefits …

β-coronavirus (CoVs) alone has been responsible for three major global outbreaks in the
21st century. The current crisis has led to an urgent requirement to develop therapeutics …

Terpenoid glycosides have significant curative effects on many kinds of diseases. Most of
these compounds are derived from medicinal plants. Glycosylation is a key step in the …

Uridine diphosphate-dependent glycosyltransferases (UGTs) in plants catalyze O-, C-, S-
and N-glycosylation of diverse substrates to yield a wide variety of glycosides with broad …

Triterpenoids are a class of natural products widely used in fields related to medicine and
health due to their biological activities such as hepatoprotection, anti-inflammation, anti-viral …

Introduction Alkaloids and glycosides are the active ingredients of the herb Dendrobium
nobile, which is used in traditional Chinese medicine. The pharmacological effects of …