Cell deformability plays an important role in cellular processes and functions, including cell
growth and differentiation, as well as cell transfer and cell cycle. Measuring deformability at …

Biological cells, by definition, are the basic units which contain the fundamental molecules of
life of which all living things are composed. Understanding how they function and …

Combining microfluidics technology with machine learning represents an innovative
approach to conduct massive quantitative cell behavior study and implement smart decision …

Abnormal red blood cell (RBC) deformability contributes to hemolysis, thrombophilia,
inflammation, and microvascular occlusion in various circulatory diseases. A quantitative …

In many medical disciplines, red blood cells are discovered to be biomarkers since they
“experience” various conditions in basically all organs of the body. Classical examples are …

Sickle cell disease (SCD) is an autosomal hereditary recessive disorder caused by a point
mutation in the β globin gene resulting in a Glu-to-Val substitution at the 6 th position of the β …

Alterations in the deformability of red blood cells (RBCs), occurring in hemolytic blood
disorders such as sickle cell disease (SCD), contribute to vaso-occlusion and disease …

Characterization of blood flow rheology in hematological disorders is critical for
understanding disease pathophysiology. Existing methods to measure blood rheological …

In this article, we describe the general features of red blood cell membranes and their effect
on blood flow and blood rheology. We first present a basic description of membranes and …

Previous on‐chip technologies for characterizing the cellular mechanical properties often
suffer from a low throughput and limited sensitivity. Herein, an inertial multi‐force …