Near‐infrared‐light‐activatable nanomaterial‐mediated phototheranostic nanomedicines: an emerging paradigm for cancer treatment
R Vankayala, KC Hwang - Advanced Materials, 2018 - Wiley Online Library
Cancer is one of the most deadly diseases threatening the lives of humans. Although many
treatment methods have been developed to tackle cancer, each modality of cancer treatment …
treatment methods have been developed to tackle cancer, each modality of cancer treatment …
The mechanistic targets of antifungal agents: an overview
TK Mazu, BA Bricker, H Flores-Rozas… - Mini reviews in …, 2016 - ingentaconnect.com
Pathogenic fungi are a major causative group for opportunistic infections (OIs). AIDS
patients and other immunocompromised individuals are at risk for OIs, which if not treated …
patients and other immunocompromised individuals are at risk for OIs, which if not treated …
Antifungals: mechanism of action and drug resistance
There are currently few antifungals in use which show efficacy against fungal diseases.
These antifungals mostly target specific components of fungal plasma membrane or its …
These antifungals mostly target specific components of fungal plasma membrane or its …
[HTML][HTML] Molecular Mechanisms of Action of Herbal Antifungal Alkaloid Berberine, in Candida albicans
S Dhamgaye, F Devaux, P Vandeputte… - PLoS …, 2014 - journals.plos.org
Candida albicans causes superficial to systemic infections in immuno-compromised
individuals. The concomitant use of fungistatic drugs and the lack of cidal drugs frequently …
individuals. The concomitant use of fungistatic drugs and the lack of cidal drugs frequently …
Curcumin targets cell wall integrity via calcineurin-mediated signaling in Candida albicans
A Kumar, S Dhamgaye, IK Maurya… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Curcumin (CUR) shows antifungal activity against a range of pathogenic fungi, including
Candida albicans. The reported mechanisms of action of CUR include reactive oxygen …
Candida albicans. The reported mechanisms of action of CUR include reactive oxygen …
[HTML][HTML] Protective Effect of Emblica officinalis in Cyprinus carpio against Hepatotoxicity Induced by Malachite Green: Ultrastructural and Molecular Analysis
Malachite green (MG) dye, besides coloring is used as an effective aquaculture therapeutic.
The present study assesses the mitigating ability of Emblica officinalis (EO) fruit extract …
The present study assesses the mitigating ability of Emblica officinalis (EO) fruit extract …
RNA Enrichment Method for Quantitative Transcriptional Analysis of Pathogens In Vivo Applied to the Fungus Candida albicans
In vivo transcriptional analyses of microbial pathogens are often hampered by low
proportions of pathogen biomass in host organs, hindering the coverage of full pathogen …
proportions of pathogen biomass in host organs, hindering the coverage of full pathogen …
Novel role of a family of major facilitator transporters in biofilm development and virulence of Candida albicans
The QDR (quinidine drug resistance) family of genes encodes transporters belonging to the
MFS (major facilitator superfamily) of proteins. We show that QDR transporters, which are …
MFS (major facilitator superfamily) of proteins. We show that QDR transporters, which are …
Clotrimazole as a potent agent for treating the oomycete fish pathogen Saprolegnia parasitica through inhibition of sterol 14α-demethylase (CYP51)
AGS Warrilow, CM Hull, NJ Rolley… - Applied and …, 2014 - Am Soc Microbiol
ABSTRACT A candidate CYP51 gene encoding sterol 14α-demethylase from the fish
oomycete pathogen Saprolegnia parasitica (SpCYP51) was identified based on conserved …
oomycete pathogen Saprolegnia parasitica (SpCYP51) was identified based on conserved …
Quinidine drug resistance transporter knockout Candida cells modulate glucose transporter expression and accumulate metabolites leading to enhanced azole drug …
ATP-binding cassette (ABC) and Major Facilitator Superfamily (MFS) transporters have been
known to play an important role in the development of multidrug resistance (MDR) in various …
known to play an important role in the development of multidrug resistance (MDR) in various …