Radiotherapy and immunology
The majority of cancer patients receive radiotherapy during the course of treatment,
delivered with curative intent for local tumor control or as part of a multimodality regimen …
delivered with curative intent for local tumor control or as part of a multimodality regimen …
Clinical Outcomes and Molecular Predictors of Pembrolizumab (Keytruda) as a PD-1 Immune Checkpoint Inhibitor in Advanced and Metastatic Cervical Cancer: A …
L Balan, AM Cimpean, PS Nandarge, B Sorop, C Balan… - Biomedicines, 2024 - mdpi.com
This systematic review evaluates the clinical outcomes and molecular predictors of response
to pembrolizumab in patients with advanced and metastatic cervical cancer. We adhered to …
to pembrolizumab in patients with advanced and metastatic cervical cancer. We adhered to …
Development of pharmacological immunoregulatory anti-cancer therapeutics: current mechanistic studies and clinical opportunities
N Yin, X Li, X Zhang, S Xue, Y Cao… - … and Targeted Therapy, 2024 - nature.com
Immunotherapy represented by anti-PD-(L) 1 and anti-CTLA-4 inhibitors has revolutionized
cancer treatment, but challenges related to resistance and toxicity still remain. Due to the …
cancer treatment, but challenges related to resistance and toxicity still remain. Due to the …
[HTML][HTML] New frontiers in locally advanced cervical cancer treatment
R Massobrio, L Bianco, B Campigotto… - Journal of Clinical …, 2024 - mdpi.com
Despite the introduction of targeted vaccines and screening protocols, locally advanced
cervical cancer represents a median proportion of 37% among all cervical carcinomas …
cervical cancer represents a median proportion of 37% among all cervical carcinomas …
Efficacy and safety of chemoradiotherapy plus immune checkpoint inhibitors for the treatment of locally advanced cervical cancer: a systematic review and meta …
Z Zhao, J Ruan, M Fang, J Liu, G Liao - Frontiers in Immunology, 2024 - frontiersin.org
Background Radiotherapy plus concurrent chemotherapy is a standard method for treating
locally advanced cervical cancer (LACC). Immune checkpoint inhibitors (ICIs) are widely …
locally advanced cervical cancer (LACC). Immune checkpoint inhibitors (ICIs) are widely …
[HTML][HTML] Entangled Connections: HIV and HPV Interplay in Cervical Cancer—A Comprehensive Review
G Pavone, A Marino, V Fisicaro, L Motta… - International Journal of …, 2024 - mdpi.com
Cervical cancer (CC) remains a prevalent malignancy and a significant global public health
concern, primarily driven by persistent human papillomavirus (HPV) infections. The …
concern, primarily driven by persistent human papillomavirus (HPV) infections. The …
A new treatment approach of toripalimab in combination with concurrent platinum‐based chemoradiotherapy for locally advanced cervical cancer: A phase II clinical …
J Chen, J Shi, Y Cao, C Li, J Li… - International Journal of …, 2024 - Wiley Online Library
This study investigated the efficacy and safety of toripalimab in combination with concurrent
platinum‐based chemoradiation in patients with untreated locally advanced cervical cancer …
platinum‐based chemoradiation in patients with untreated locally advanced cervical cancer …
Toripalimab combined with definitive chemoradiotherapy for locally advanced cervical squamous cell carcinoma patients (TRACE): A single-arm, phase I/II trial
D Ou, R Cai, WX Qi, C Cui, L Cao, SB Wang… - Cancer Immunology …, 2024 - Springer
Abstract Purpose This phase I/II trial (ChiCTR2000032879) assessed the safety and efficacy
of toripalimab combined with chemoradiotherapy for locally advanced cervical squamous …
of toripalimab combined with chemoradiotherapy for locally advanced cervical squamous …
[HTML][HTML] The prognostic value of Th17/Treg cell in cervical cancer: a systematic review and meta-analysis
J Zhang, J Zhan, Z Guan, X Lin, T Li, M Li… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Background The prognostic significance of Treg and Th17 cells, as well as their ratio
(Th17/Treg), in cervical cancer remains a topic of debate. Our study aimed to clarify their …
(Th17/Treg), in cervical cancer remains a topic of debate. Our study aimed to clarify their …
Unmet needs in cervical cancer–can biological therapies plug the gap?
M Greenman, YE Chang, B McNamara… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Cervical cancer remains one of the most common gynecologic malignancies
worldwide. A disproportionate burden of cases occurs in developing countries due to …
worldwide. A disproportionate burden of cases occurs in developing countries due to …