Mutant TP53 proteins are thought to drive the development and sustained expansion of
cancers at least in part through the loss of the wild-type (wt) TP53 tumour suppressive …

Mantle cell lymphoma (MCL) is characterized by the t (11; 14) translocation, which leads to
deregulated expression of the cell cycle regulatory protein cyclin D1 (CCND1). Genomic …

Objective Chemoresistance is one of the major barriers in chemotherapy-based
hepatocellular carcinoma (HCC) intervention. 5-Fluorouracil (5-Fu) is a widely used as an …

Several experimental strategies in the treatment of cancer include drug alteration of cell
cycle regulatory pathways as a useful strategy. Extra-ribosomal functions of human …

The neural transcription factor SOX11 is usually highly expressed in typical mantle cell
lymphoma (MCL), but it is absent in the more indolent form of MCL. Despite being an …

Purpose The present study aimed to investigate the molecular mechanisms underlying the
anticancer properties of ginger extract (GE) in mice bearing solid Ehrlich carcinoma (SEC) …

The variable outcome to standard immunochemotherapy for mantle cell lymphoma (MCL)
patients is a clinical challenge. Established risk factors, including high MCL International …

Background/Aim: Under severe hypoxia, cellular apoptosis is induced through hypoxia-
inducible factor 1, alpha subunit (HIF-1α)-dependent P53 accumulation and P53 …

Acute myeloid leukemia (AML), characterized by extremely heterogeneous molecular and
biologic abnormalities, is an aggressive hematologic malignancy, hampering the research …

Background Burkitt lymphoma (BL) is a highly aggressive, fast-growing B-cell non-Hodgkin's
lymphoma, manifested in several subtypes, including sporadic, endemic, and …