Microglia-astrocyte crosstalk has recently been at the forefront of glial research. Emerging
evidence illustrates that microglia-and astrocyte-derived signals are the functional …

Spinal cord injury (SCI) and spinal infarction lead to neurological complications and
eventually to paraplegia or quadriplegia. These extremely debilitating conditions are major …

Microglia, resident macrophages of the CNS, are essential to brain development,
homeostasis, and disease. Microglial activation and proliferation are hallmarks of many CNS …

Background Interactions between neurons, astrocytes, and microglia critically influence
neuroinflammatory responses to insult in the central nervous system. In vitro astrocyte and …

Abstracts Bone mainly functions as a supportive framework for the whole body and is the
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …

Alzheimer's disease (AD) is a complex disorder and the most common form of
neurodegenerative dementia. Several genetic, environmental, and physiological factors …

Brain metastasis still encompass very grim prognosis and therefore understanding the
underlying mechanisms is an urgent need toward developing better therapeutic strategies …

Recent neuroscience research has established the adult brain as a dynamic organ having a
unique ability to undergo changes with time. Neuroglia, especially microglia and astrocytes …

Autophagy is a catabolic process that degrades cytoplasmic constituents and organelles in
the lysosome, thus serving an important role in cellular homeostasis and protection against …

Neuroinflammation and epilepsy are interconnected. Brain inflammation promotes neuronal
hyper-excitability and seizures, and dysregulation in the glia immune-inflammatory function …