Hybridoma technology a versatile method for isolation of monoclonal antibodies, its applicability across species, limitations, advancement and future perspectives

HA Parray, S Shukla, S Samal, T Shrivastava… - International …, 2020 - Elsevier
The advancements in technology and manufacturing processes have allowed the
development of new derivatives, biosimilar or advanced improved versions for approved …

[HTML][HTML] Molecular properties of human IgG subclasses and their implications for designing therapeutic monoclonal antibodies against infectious diseases

V Irani, AJ Guy, D Andrew, JG Beeson… - Molecular …, 2015 - Elsevier
Monoclonal antibodies are being developed as therapeutics to complement drugs and
vaccines or to fill the gap where no drugs or vaccines exist. These therapeutic antibodies …

Aerosol-jet-printed graphene electrochemical immunosensors for rapid and label-free detection of SARS-CoV-2 in saliva

CC Pola, SV Rangnekar, R Sheets… - 2D …, 2022 - iopscience.iop.org
Rapid, inexpensive, and easy-to-use coronavirus disease 2019 (COVID-19) home tests are
key tools in addition to vaccines in the world wide fight to eliminate national and local …

[HTML][HTML] Citrullinated histone H3 as a therapeutic target for endotoxic shock in mice

Q Deng, B Pan, HB Alam, Y Liang, Z Wu, B Liu… - Frontiers in …, 2020 - frontiersin.org
Sepsis results in millions of deaths every year, with acute lung injury (ALI) being one of the
leading causes of mortality in septic patients. As neutrophil extracellular traps (NETs) are …

[HTML][HTML] Pre-stage perfusion and ultra-high seeding cell density in CHO fed-batch culture: a case study for process intensification guided by systems biotechnology

L Stepper, FA Filser, S Fischer, J Schaub, I Gorr… - Bioprocess and …, 2020 - Springer
Process intensification strategies are needed in the field of therapeutic protein production for
higher productivities, lower cost of goods and improved facility utilization. This work …

[HTML][HTML] Retrospective analysis of the preparation and application of immunotherapy in cancer treatment

J Lu, J Ding, Z Liu, T Chen - … Journal of Oncology, 2022 - spandidos-publications.com
Monoclonal antibody technology plays a vital role in biomedical and immunotherapy, which
greatly promotes the study of the structure and function of genes and proteins. To date …

Plant‐produced monoclonal antibody as immunotherapy for cancer

MU Nessa, MA Rahman, Y Kabir - BioMed Research …, 2020 - Wiley Online Library
Plant‐based products have expanded to include cancer immunotherapy, which has made
great strides over recent years. Plants are considered inexpensive and facile production …

Influenza therapeutics in clinical practice—challenges and recent advances

JH Beigel, FG Hayden - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
In the last few years, several new direct-acting influenza antivirals have been licensed, and
others have advanced in clinical development. The increasing diversity of antiviral classes …

[HTML][HTML] A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages

C Schafer, N Dambrauskas, RW Steel, S Carbonetti… - Malaria journal, 2018 - Springer
Background Plasmodium vivax is the most geographically widespread of the human malaria
parasites, causing 50,000 to 100,000 deaths annually. Plasmodium vivax parasites have the …

Drug-drug interactions between COVID-19 drug therapies and antidepressants

E Davoutis, C Panou, N Stachika, C Dalla… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Antidepressants are widely used for the pharmacological treatment of anxiety
and mood disorders. Since the eruption of the SARS-COV-2 pandemic and the later …