MRI contrast agents: basic chemistry and safety

D Hao, T Ai, F Goerner, X Hu… - Journal of Magnetic …, 2012 - Wiley Online Library
Magnetic resonance imaging (MRI) contrast agents are pharmaceuticals used widely in MRI
examinations. Gadoliniumbased MRI contrast agents (GBCAs) are by far the most …

Adverse reactions to gadoterate meglumine: review of over 25 years of clinical use and more than 50 million doses

E de Kerviler, K Maravilla, JF Meder… - Investigative …, 2016 - journals.lww.com
Objective The aim of this study was to evaluate the safety profile of gadoterate meglumine
from clinical trials, postmarketing observational studies, and pharmacovigilance reports of …

Observational study on the safety profile of gadoterate meglumine in 35,499 patients: The SECURE study

P Soyer, A Dohan, D Patkar… - Journal of Magnetic …, 2017 - Wiley Online Library
Purpose To investigate the safety of gadoterate meglumine and identify the incidence of
nephrogenic systemic fibrosis (NSF). Materials and Methods An international prospective …

Recurrent peripheral vestibulopathy: Is MRI useful for the diagnosis of endolymphatic hydrops in clinical practice?

A Attyé, G Dumas, I Troprès, M Roustit, A Karkas… - European …, 2015 - Springer
Objectives Recurrent peripheral vestibulopathy (RPV) is a public health problem, yet the
aetiology remains unclear. Recent developments in MRI of endolymphatic hydrops (EH) …

[HTML][HTML] Gadolinium-based contrast agents for imaging of the central nervous system: A multicenter European prospective study

AH Behzadi, J McDonald - Medicine, 2022 - journals.lww.com
Abstract Contrast-enhanced MR (CE-MR) imaging is required to improve lesion detection
and characterization and to increase diagnostic confidence. This study aims to evaluate the …

[HTML][HTML] Safety of gadobutrol in over 23,000 patients: the GARDIAN study, a global multicentre, prospective, non-interventional study

MR Prince, HG Lee, CH Lee, SW Youn, IH Lee… - European …, 2017 - Springer
Objectives To investigate the safety and tolerability of gadobutrol at the recommended dose
in patients requiring contrast-enhanced magnetic resonance imaging/angiography …

[HTML][HTML] Safety of meglumine gadoterate (Gd-DOTA)-enhanced MRI compared to unenhanced MRI in patients with chronic kidney disease (RESCUE study)

G Deray, O Rouviere, L Bacigalupo, B Maes… - European …, 2013 - Springer
Objective To prospectively compare the renal safety of meglumine gadoterate (Gd-DOTA)-
enhanced magnetic resonance imaging (MRI) to a control group (unenhanced MRI) in high …

[HTML][HTML] Patterns of use, effectiveness and safety of gadolinium contrast agents: a European prospective cross-sectional multicentre observational study

JÅ Jakobsen, CC Quattrocchi, FHH Müller… - BMC Medical …, 2021 - Springer
Background The EU gadolinium-based contrast agents (GBCA) market has changed in
recent years due to the European Medicines Agency decision to suspend the marketing …

[HTML][HTML] Safety of gadobutrol: results from 42 clinical phase II to IV studies and postmarketing surveillance after 29 million applications

J Endrikat, K Vogtlaender, S Dohanish… - Investigative …, 2016 - journals.lww.com
Objective The aim of this study was to provide a systematic safety analysis of gadobutrol
after more than 29 million applications in clinical routine. Materials and Methods Forty-two …

Safety of magnetic resonance contrast media: a review with special focus on nephrogenic systemic fibrosis

S Haneder, W Kucharczyk… - Topics in Magnetic …, 2015 - journals.lww.com
Magnetic resonance imaging contrast agents can be classified according to their chemical
structures, their effect on the local magnetic field, or by their contrast mechanism. Two main …