Lipid and immune pathways are crucial in the pathophysiology of metabolic and
cardiovascular disease. Arachidonic acid (AA) and its derivatives link nutrient metabolism to …

Studies reporting blood levels of the omega-3 polyunsaturated fatty acids, eicosapentaenoic
acid (EPA) and docosahexaenoic acid (DHA), were systematically identified in order to …

The metabolic state represents a major hurdle for an effective adoptive T cell therapy (ACT).
Indeed, specific lipids can harm CD8+ T cell (CTL) mitochondrial integrity, leading to …

Ferroptosis is a form of regulated cell death characterized by iron-dependent lipid
peroxidation. This process contributes to cellular and tissue damage in various human …

Fatty acids play critical roles in biological systems. Imbalances in fatty acids are related to a
variety of diseases, which makes the measurement of fatty acids in biological samples …

The liver metabolizes ethanol through three enzymatic pathways: alcohol dehydrogenase
(ADH), cytochrome p450 (also called MEOS), and catalase. Alcohol dehydrogenase class I …

Obesity promotes diverse pathologies, including atherosclerosis and dementia, which
frequently involve vascular defects and endothelial cell (EC) dysfunction. Each organ has …

Fatty acid uptake and altered metabolism constitute hallmarks of metastasis,, yet evidence of
the underlying biology, as well as whether all dietary fatty acids are prometastatic, is lacking …

Type 2 diabetes mellitus (T2DM) is characterised by chronic low-grade inflammation,
recently referred to as 'metaflammation', a relevant factor contributing to the development of …

Fatty acid synthase (FASN) predominantly generates straight-chain fatty acids using acetyl-
CoA as the initiating substrate. However, monomethyl branched-chain fatty acids …