The Escherichia coli heat shock response (HSR) is a complex mechanism triggered by heat
shock and by a variety of other growth-impairing stresses. We explore here the potential use …

Temperature is a ubiquitous physical cue that is non-invasive, penetrative and easy to apply.
In the growing field of thermogenetics, through beneficial repurposing of natural …

Hydroxycinnamic acids and curcumin are compounds with great therapeutic potential,
including anticancer properties. In this study, p-coumaric acid, caffeic acid and curcumin …

The overproduction of recombinant proteins in Escherichia coli leads to insoluble
aggregates of proteins called inclusion bodies (IBs). IBs are considered dynamic entities that …

Recombinant protein (RP) production from Escherichia coli has been extensively studied to
find strategies for increasing product yields. The thermoinducible expression system is …

The heat-inducible expression system has been widely used to produce recombinant
proteins in Escherichia coli. However, the rise in temperature affects cell growth, activates …

Background The temperature upshift has been widely used as an induction system to
produce recombinant proteins (RPs). However, thermoinduction could affect bacterial …

Abstract (S)-3-chloro-1-phenyl-1-propanol ((S)-CPPO) is an important chiral intermediate
predominantly used in the synthesis of the chiral side chain of (S)-fluoxetine. In this study …

Aggregation of recombinant proteins into inclusion bodies (IBs) is the major drawback of
heterologous expression in Escherichia coli. Here, we evaluated the effects of a pH shift …

The effect of gradients of elevated glucose and low dissolved oxygen in the addition zone of
fed-batch E. coli thermoinduced recombinant high cell density cultures can be evaluated …