Advances in the clinical treatment of multidrug-resistant pathogens using polymyxins

Y Huang, M Liao, X Hu, H Hu… - Journal of Antimicrobial …, 2024 - academic.oup.com
Objectives Polymyxins are a vital class of antibiotics used to combat multidrug-resistant
Gram-negative bacteria. However, their use is limited due to potential nephrotoxicity and the …

Pharmacokinetics and safety of colistin sulfate after single and multiple intravenous doses in healthy Chinese subjects

X Huang, X Liu, Y Fan, Y Wang, B Guo, J Wang… - International Journal of …, 2024 - Elsevier
Objective Increasing antimicrobial resistance has led to the revival of the polymyxins as a
last-resort therapeutic option for multidrug-resistant Gram-negative bacterial infections. A …

Risk factors and prognosis for the development of acute kidney injury in patients using colistin in the intensive care unit: A retrospective cohort study

M Deniz, M Alişik - Medicine, 2024 - journals.lww.com
Colistin, an antibiotic of polymyxin group, has recently been increasingly used in the
treatment of multidrug resistant gram-negative bacteria. However, it has serious adverse …

[PDF][PDF] Polymyxins leading to nephrotoxicity.

S Lolla, SN Uddin, C Supriya… - International Journal of …, 2023 - researchgate.net
Polymyxins leading to nephrotoxicity Page 1 International Journal of Basic & Clinical
Pharmacology | November-December 2023 | Vol 12 | Issue 6 Page 874 International Journal of …