Traditionally, tumor-associated lymphatic vessels have been regarded as passive by-
standers, serving simply as a drainage system for interstitial fluid generated within the tumor …

Objective The lymphovascular invasion (LVI) has been reported as a prognosis predictor in
multiple cancers. The aim of this meta-analysis was to investigate the potential value of LVI …

Background Risks of perineural invasion (PNI) in T1‐2 oral tongue squamous cell
carcinoma (SCC) have not been specifically elucidated. Methods Pathological features …

Cervical lymph node metastases reduce the overall survival of patients with oral squamous
cell carcinoma (OSCC) and require a neck dissection. However, elective management of a …

Tumor-associated lymphatic vessels play an important role in tumor progression, mediating
lymphatic dissemination of malignant cells to tumor-draining lymph nodes and regulating …

Increasing evidence has shown that chemo-resistance is related to the process of epithelial-
mesenchymal transition (EMT) and increased invasiveness by tongue squamous cell …

In patients with early head and neck squamous cell carcinoma (HNSCC), occult lymph node
metastasis is difficult to predict by clinical or pathological parameters. However, such …

Background Prognostic factors in predicting occult lymph node metastasis in patients with
head and neck squamous-cell carcinoma (HNSCC) are necessary to improve the results of …

Background There have been few recent advances in the identification of occult lymph node
metastases (OLNM) in oral squamous cell carcinoma (OSCC). This study aimed to develop …

BACKGROUND: The transcription factor sex determining region Y (SRY)-box 2
(SOX2)(3q26. 3–q27) has been recently identified as a recurrently activated major …