Invasive candidiasis (IC) is a significant cause of morbidity and mortality. Diagnosis relies on
culture-based methods, which lack sensitivity and delay diagnosis. We conducted a …

Introduction intra-abdominal candidiasis (IAC) may include Candida involvement of
peritoneum or intra-abdominal abscess and is burdened by high morbidity and mortality …

Introduction The term invasive candidiasis (IC) refers to both bloodstream and deep-seated
invasive infections, such as peritonitis, caused by Candida species. Several guidelines on …

Importance Although frequently used in treating intensive care unit (ICU) patients with
sepsis, empirical antifungal therapy, initiated for suspected fungal infection, has not been …

Background Invasive candidiasis and candidemia are frequently encountered in the
nosocomial setting particularly in the intensive care unit (ICU). Objective and methods To …

Despite the availability of newer antifungal drugs, outcomes for patients with invasive fungal
infections (IFIs) continue to be poor, in large part due to delayed diagnosis and initiation of …

Objectives Although inadequate antimicrobial therapy has been demonstrated in multiple
studies to increase the risk for death in bacterial infections, few data investigating the effect …

Background: Invasive infection with Candida species is an important cause of morbidity and
mortality in intensive care unit (ICU) patients. Optimal preventive strategies have not been …

Advances in critical care, operative techniques, early fluid resuscitation, antimicrobials to
control bacterial infections, nutritional support to manage the hypermetabolic response and …

Abstract Purpose of Review The use of molecular tests to aid the diagnosis of invasive yeast
infection, in particular invasive candidosis, has been described for over two decades, yet …