[HTML][HTML] Human disorders of peroxisome metabolism and biogenesis
HR Waterham, S Ferdinandusse… - Biochimica Et Biophysica …, 2016 - Elsevier
Peroxisomes are dynamic organelles that play an essential role in a variety of cellular
catabolic and anabolic metabolic pathways, including fatty acid alpha-and beta-oxidation …
catabolic and anabolic metabolic pathways, including fatty acid alpha-and beta-oxidation …
Plasmalogens: A potential therapeutic target for neurodegenerative and cardiometabolic disease
Plasmalogens are a class of membrane glycerophospholipids with unique properties. They
contain a vinyl-ether linked alkyl chain at the sn-1 position of the glycerol backbone and …
contain a vinyl-ether linked alkyl chain at the sn-1 position of the glycerol backbone and …
Biochemistry of mammalian peroxisomes revisited
RJA Wanders, HR Waterham - Annu. Rev. Biochem., 2006 - annualreviews.org
In this review, we describe the current state of knowledge about the biochemistry of
mammalian peroxisomes, especially human peroxisomes. The identification and …
mammalian peroxisomes, especially human peroxisomes. The identification and …
Mechanisms of plant salt response: insights from proteomics
Soil salinity is a major abiotic stress that limits plant growth and agriculture productivity. To
cope with salt stress, plants have evolved complex salt-responsive signaling and metabolic …
cope with salt stress, plants have evolved complex salt-responsive signaling and metabolic …
Zellweger spectrum disorders: clinical overview and management approach
FCC Klouwer, K Berendse, S Ferdinandusse… - Orphanet journal of rare …, 2015 - Springer
Zellweger spectrum disorders (ZSDs) represent the major subgroup within the peroxisomal
biogenesis disorders caused by defects in PEX genes. The Zellweger spectrum is a clinical …
biogenesis disorders caused by defects in PEX genes. The Zellweger spectrum is a clinical …
Functions and biosynthesis of plasmalogens in health and disease
P Brites, HR Waterham, RJA Wanders - … BBA)-Molecular and Cell Biology of …, 2004 - Elsevier
Plasmalogens (1-O-alk-1′-enyl-2-acyl glycerophospholipids) constitute a special class of
phospholipids characterized by the presence of a vinyl–ether bond at the sn-1 position …
phospholipids characterized by the presence of a vinyl–ether bond at the sn-1 position …
[HTML][HTML] Genetics and molecular basis of human peroxisome biogenesis disorders
HR Waterham, MS Ebberink - … et Biophysica Acta (BBA)-Molecular Basis of …, 2012 - Elsevier
Human peroxisome biogenesis disorders (PBDs) are a heterogeneous group of autosomal
recessive disorders comprised of two clinically distinct subtypes: the Zellweger syndrome …
recessive disorders comprised of two clinically distinct subtypes: the Zellweger syndrome …
Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5
Many proteins contain targeting signals within their sequences that specify their delivery to
particular organelles. The peroxisomal targeting signal-1 (PTS1) is a C-terminal tripeptide …
particular organelles. The peroxisomal targeting signal-1 (PTS1) is a C-terminal tripeptide …
The Arabidopsis pxa1 Mutant Is Defective in an ATP-Binding Cassette Transporter-Like Protein Required for Peroxisomal Fatty Acid β-Oxidation
Peroxisomes are important organelles in plant metabolism, containing all the enzymes
required for fatty acid β-oxidation. More than 20 proteins are required for peroxisomal …
required for fatty acid β-oxidation. More than 20 proteins are required for peroxisomal …
[HTML][HTML] Hair follicle stem cell-specific PPARγ deletion causes scarring alopecia
P Karnik, Z Tekeste, TS McCormick, AC Gilliam… - Journal of Investigative …, 2009 - Elsevier
Primary cicatricial or scarring alopecias (CA) are a group of inflammatory hair disorders of
unknown pathogenesis characterized by the permanent destruction of the hair follicle. The …
unknown pathogenesis characterized by the permanent destruction of the hair follicle. The …