Beyond cisplatin: New frontiers in metallodrugs for hard-to-treat triple negative breast cancer

N Muhammad, M Hanif, P Yang - Coordination Chemistry Reviews, 2024 - Elsevier
Triple-negative breast cancer (TNBC) is the most aggressive and hard-to-treat form of breast
cancer. TNBC has a higher propensity for earlier relapse and an increased risk of metastasis …

Platinum (IV) and platinum (II) anticancer complexes with biologically active releasable ligands

P Štarha, R Křikavová - Coordination Chemistry Reviews, 2024 - Elsevier
The concept of multi-action octahedral platinum (IV) complexes is based on the rational
derivatization of anticancer square-planar platinum (II) compounds (eg, cisplatin or …

Intracellular localization studies of the luminescent analogue of an anticancer ruthenium iminophosphorane with high efficacy in a triple-negative breast cancer mouse …

K Miachin, V Del Solar, E El Khoury, N Nayeem… - Inorganic …, 2021 - ACS Publications
The potential of ruthenium (II) compounds as an alternative to platinum-based clinical
anticancer agents has been unveiled after extensive research for over 2 decades. As …

[HTML][HTML] Mitochondrial DNA-targeted therapy: A novel approach to combat cancer

Y Lin, B Yang, Y Huang, Y Zhang, Y Jiang, L Ma… - Cell Insight, 2023 - Elsevier
Mitochondrial DNA (mtDNA) encodes proteins and RNAs that are essential for mitochondrial
function and cellular homeostasis, and participates in important processes of cellular …

Regulation of Bacterial Behavior by Light and Magnetism Mediated by Mesoporous Silica-Coated MnFe2O4@CoFe2O4 Nanoparticles

T Deng, FC Lin, JI Zink, Q Yu - ACS Applied Materials & Interfaces, 2022 - ACS Publications
Unicellular bacterial cells exhibit diverse population behaviors (ie, aggregation, dispersion,
directed assembly, biofilm formation, etc.) to facilitate communication and cooperation …

Platinum (IV)-based prodrugs as an alternative to Pt (II)-based drugs: synthesis and biological action

DV Spector, AA Bubley, EK Beloglazkina… - Uspehi …, 2023 - journals.rcsi.science
The chemotherapy with cisplatin and its analogues widely used in medical practice is
associated with undesirable side effects caused by non-selective ligand exchange and …

[PDF][PDF] Wpływ indukowanej stresem oksydacyjnym aktywacji ścieżki sygnalizacyjnej białka p66Shc na mitochondrialne parametry bioenergetyczne i poziom …

M Prill - 2022 - rcin.org.pl
Mitochondria pełnią szereg niezwykle istotnych funkcji w komórce takich jak synteza ATP
czy produkcja reaktywnych form tlenu. Są one również zaangażowane w wiele kluczowych …