The food metabolome is defined as the part of the human metabolome directly derived from
the digestion and biotransformation of foods and their constituents. With> 25,000 …

Abstract Background and Purpose It used to be a common practice in the field of nutritional
epidemiology to analyze separate nutrients, foods, or food groups. However, in reality …

Type 2 diabetes (T2D) can be prevented in pre‐diabetic individuals with impaired glucose
tolerance (IGT). Here, we have used a metabolomics approach to identify candidate …

Abstract The Generation R Study is a population-based prospective cohort study from fetal
life until adulthood. The study is designed to identify early environmental and genetic causes …

Background: Healthy dietary patterns that conform to national dietary guidelines are related
to lower chronic disease incidence and longer life span. However, the precise mechanisms …

Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

Background Information regarding the variability of metabolite levels over time in an
individual is required to estimate the reproducibility of metabolite measurements. In …

Advances in laboratory sciences offer much in the challenge to unravel the complex etiology
of cancer and to therefore provide an evidence‐base for prevention. One area where …

Using dietary biomarkers in nutritional epidemiological studies may better capture exposure
and improve the level at which diet-disease associations can be established and explored …

Previously, we have identified the branched chain amino-acid transaminase 1 (BCAT1)
gene as notably hypomethylated in low-malignant potential (LMP) and high-grade (HG) …