Inflammatory breast cancer (IBC) is a rare and aggressive disease that accounts for~ 2–4%
of all breast cancers. However, despite its low incidence rate, IBC is responsible for 7–10 …

Therapeutic resistance has been and remains to be the major challenge in developing
successful treatments for different cancers and therefore, understanding the underlying …

Inflammation, and the organization of collagen in the breast tumor microenvironment, is an
important mediator of breast tumor progression. However, a direct link between markers of …

Nasopharyngeal carcinoma (NPC) has the highest rate of metastasis among head and neck
cancers, and distant metastasis is the major reason for treatment failure. We have previously …

An important feature shared by many cancer cells is drastically altered metabolism that is
critical for rapid growth and proliferation. The distinctly reprogrammed metabolism in cancer …

Cancer remains the second leading cause of death in the US, accounting for 25% of all
deaths nationwide. Immunotherapy techniques bolster the immune cells' ability to target …

Pre‑clinical and on‑going trials have indicated the advantage of using metformin as an
anticancer drug alone or in combination with other chemotherapeutics for the treatment of …

Purpose: B-cell lymphoma 2 (BCL2) is an antiapoptosis protein and an important clinical
breast cancer prognostic marker. As the role of BCL2 is dependent on the estrogen receptor …

Preclinical studies have shown positive effects of statins against specific cancers. This study
aimed to determine the therapeutic effect of simvastatin in 12‐dimethylbenz (a) anthracene …

Inflammation of the adipose tissues occurs in association with obesity. This inflammatory
process leads to the induction of cyclooxygenase-2 (COX-2) expression and a consequent …