Glycogen synthesis and beyond, a comprehensive review of GSK3 as a key regulator of metabolic pathways and a therapeutic target for treating metabolic diseases
L Wang, J Li, L Di - Medicinal Research Reviews, 2022 - Wiley Online Library
Abstract Glycogen synthase kinase‐3 (GSK3) is a highly evolutionarily conserved
serine/threonine protein kinase first identified as an enzyme that regulates glycogen …
serine/threonine protein kinase first identified as an enzyme that regulates glycogen …
Muscle wasting and aging: experimental models, fatty infiltrations, and prevention
Identification of cost-effective interventions to maintain muscle mass, muscle strength, and
physical performance during muscle wasting and aging is an important public health …
physical performance during muscle wasting and aging is an important public health …
Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation
V Marion, C Stoetzel, D Schlicht… - Proceedings of the …, 2009 - National Acad Sciences
Bardet-Biedl syndrome (BBS) is an inherited ciliopathy generally associated with severe
obesity, but the underlying mechanism remains hypothetical and is generally proposed to be …
obesity, but the underlying mechanism remains hypothetical and is generally proposed to be …
Activin a plays a critical role in proliferation and differentiation of human adipose progenitors
LE Zaragosi, B Wdziekonski, P Villageois… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Growth of white adipose tissue takes place in normal development and in
obesity. A pool of adipose progenitors is responsible for the formation of new adipocytes and …
obesity. A pool of adipose progenitors is responsible for the formation of new adipocytes and …
Multi-lineage differentiation of mesenchymal stem cells–To Wnt, or not Wnt
Mesenchymal stem cells (MSCs) are multipotent precursor cells originating from several
adult connective tissues. MSCs possess the ability to self-renew and differentiate into …
adult connective tissues. MSCs possess the ability to self-renew and differentiate into …
SPARC inhibits adipogenesis by its enhancement of β-catenin signaling
J Nie, EH Sage - Journal of Biological Chemistry, 2009 - ASBMB
SPARC (secreted protein acidic and rich in cysteine) modulates interactions between cells
and extracellular matrix and is enriched in white adipose tissue. We have reported that …
and extracellular matrix and is enriched in white adipose tissue. We have reported that …
[HTML][HTML] Wnt signaling behaves as a “master regulator” in the osteogenic and adipogenic commitment of human amniotic fluid mesenchymal stem cells
I D'Alimonte, A Lannutti, C Pipino, P Di Tomo… - Stem Cell Reviews and …, 2013 - Springer
Human amniotic fluid mesenchymal stem cells (huAFMSCs) are emerging as a promising
therapeutic option in regenerative medicine. Here, we characterized huAFMSC phenotype …
therapeutic option in regenerative medicine. Here, we characterized huAFMSC phenotype …
Circadian clock genes modulate human bone marrow mesenchymal stem cell differentiation, migration and cell cycle
H Boucher, V Vanneaux, T Domet, A Parouchev… - PLoS …, 2016 - journals.plos.org
Many of the components that regulate the circadian clock have been identified in organisms
and humans. The influence of circadian rhythm (CR) on the regulation of stem cells biology …
and humans. The influence of circadian rhythm (CR) on the regulation of stem cells biology …
High throughput transcriptome profiling of lithium stimulated human mesenchymal stem cells reveals priming towards osteoblastic lineage
Human mesenchymal stem cells (hMSCs) present in the bone marrow are the precursors of
osteoblasts, chondrocytes and adipocytes, and hold tremendous potential for …
osteoblasts, chondrocytes and adipocytes, and hold tremendous potential for …
Metabolic contributions of Wnt signaling: more than controlling flight
F Abou Azar, GE Lim - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
The canonical Wnt signaling pathway is ubiquitous throughout the body and influences a
diverse array of physiological processes. Following the initial discovery of the Wnt signaling …
diverse array of physiological processes. Following the initial discovery of the Wnt signaling …