Biorefineries for the production of top building block chemicals and their derivatives

S Choi, CW Song, JH Shin, SY Lee - Metabolic engineering, 2015 - Elsevier
Due to the growing concerns on the climate change and sustainability on petrochemical
resources, DOE selected and announced the bio-based top 12 building blocks and …

Valorization of industrial waste and by-product streams via fermentation for the production of chemicals and biopolymers

AA Koutinas, A Vlysidis, D Pleissner… - Chemical Society …, 2014 - pubs.rsc.org
The transition from a fossil fuel-based economy to a bio-based economy necessitates the
exploitation of synergies, scientific innovations and breakthroughs, and step changes in the …

Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis

XR Jiang, X Yan, LP Yu, XY Liu, GQ Chen - Nature communications, 2021 - nature.com
Hydroxypropionic acid (3HP), an important three carbon (C3) chemical, is designated as
one of the top platform chemicals with an urgent need for improved industrial production …

Biobased organic acids production by metabolically engineered microorganisms

Y Chen, J Nielsen - Current opinion in biotechnology, 2016 - Elsevier
Highlights•The use of inexpensive carbon sources is urgently needed for citric acid
production.•Low-pH process benefits lactic acid production.•Different strains and processes …

Metabolic engineering of Corynebacterium glutamicum for the production of 3-hydroxypropionic acid from glucose and xylose

Z Chen, J Huang, Y Wu, W Wu, Y Zhang, D Liu - Metabolic Engineering, 2017 - Elsevier
Hydroxypropionic acid (3-HP) is a promising platform chemical which can be used for the
production of various value-added chemicals. In this study, Corynebacterium glutamicum …

Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source

V Kumar, S Park - Biotechnology advances, 2018 - Elsevier
Klebsiella pneumoniae is a Gram-negative facultative anaerobe that metabolizes glycerol
efficiently under both aerobic and anaerobic conditions. This microbe is considered an …

Coupled incremental precursor and co-factor supply improves 3-hydroxypropionic acid production in Saccharomyces cerevisiae

Y Chen, J Bao, IK Kim, V Siewers, J Nielsen - Metabolic engineering, 2014 - Elsevier
Hydroxypropionic acid (3-HP) is an attractive platform chemical, which can be used to
produce a variety of commodity chemicals, such as acrylic acid and acrylamide. For …

Toward glycerol biorefinery: metabolic engineering for the production of biofuels and chemicals from glycerol

Z Chen, D Liu - Biotechnology for biofuels, 2016 - Springer
As an inevitable by-product of the biofuel industry, glycerol is becoming an attractive
feedstock for biorefinery due to its abundance, low price and high degree of reduction …

Biocatalytic gateway to convert glycerol into 3-hydroxypropionic acid in waste-based biorefineries: Fundamentals, limitations, and potential research strategies

HM Zabed, S Akter, PF Rupani, J Akor, Y Zhang… - Biotechnology …, 2023 - Elsevier
Microbial conversion of bioenergy-derived waste glycerol into value-added chemicals has
emerged as an important bioprocessing technology due to its eco-friendliness, feasible …

Recent advances, challenges and metabolic engineering strategies in the biosynthesis of 3‐hydroxypropionic acid

B Liang, G Sun, X Zhang, Q Nie… - Biotechnology and …, 2022 - Wiley Online Library
As an attractive and valuable platform chemical, 3‐hydroxypropionic acid (3‐HP) can be
used to produce a variety of industrially important commodity chemicals and biodegradable …