Cell death is a fundamental physiological process in all living organisms. Processes such as
embryonic development, organ formation, tissue growth, organismal immunity, and drug …

High-grade serous ovarian carcinoma (HGSOC), the deadliest ovarian cancer, alone
accounts for 90% of all its subtypes. Characterized by hallmark mutation of TP53, HGSOC …

Ovarian high‐grade serous carcinoma (HGSC) originates in the fallopian tube, with
secretory cells carrying a TP53 mutation, known as p53 signatures, identified as potential …

Simple Summary High grade serous ovarian cancer (HGSOC) is the most common and
lethal subtype of ovarian cancer without effective therapeutic options. The high prevalence …

Toxicity and emerging drug resistance are important challenges in PARP inhibitor (PARPi)
treatment of ovarian cancer. Recent research has shown that evolutionary-inspired …

Melanoma is a melanocyte‐derived malignant cancer and is known for its early metastasis
and high mortality rates. It is a highly cutaneous tumour disease that could be related to the …

Epithelial ovarian cancer remains the lethal gynecological malignancy in women. The
representative histotype is high-grade serous carcinoma (HGSC), and most patients with …

TRPS1 is aberrantly expressed in a variety of tumors, including breast, prostate, and gastric
cancers, and is strongly associated with tumorigenesis or prognosis. However, the role of …

High grade serous ovarian cancer (HGSOC) is a lethal gynecologic malignancy in which
chemoresistant recurrence rates remain high. Furthermore, HGSOC patients have …

Ovarian cancer is one of the most lethal gynecological cancers, and 80% are high-grade
serous carcinomas (HGSOC). Despite advances in chemotherapy and the development of …