Nuclear factor erythroid 2-related factor 2 (Nrf2) is a vital transcription factor and its induction
is of significant importance for protecting against oxidative damage. Increased levels of …

Melatonin is the major secretory product synthesized and secreted by the pineal gland and
shows both a wide distribution within phylogenetically distant organisms from bacteria to …

Our daily rhythmicity is controlled by a circadian clock with a specific set of genes located in
the suprachiasmatic nucleus in the hypothalamus. Mast cells (MCs) are major effector cells …

Background Oxidative stress plays a critical role in pulmonary fibrosis after acute lung injury
(ALI), and epithelial-mesenchymal transition (EMT) events are involved in this process. The …

Fibrosis is a common occurrence following organ injury and failure. To date, there is no
effective treatment for this condition. Melatonin targets numerous molecular pathways, a …

Fibrosis, the excessive deposition of fibrous connective tissue in an organ in response to
injury, is a pathological condition affecting many individuals worldwide. Fibrosis causes the …

Objectives The present work evaluated preventive effect of curcumin on cisplatin‐induced
bladder cystopathy. Methods Fifteen female rats were divided into (i) Control group …

Vascular toxicity is one of serious complications following cisplatin‐based chemotherapy.
This case suggests that cisplatin has a potential risk of delayed occurrence of vasospastic …