Emerging role of human microbiome in cancer development and response to therapy: special focus on intestinal microflora
H Sadrekarimi, ZR Gardanova, M Bakhshesh… - Journal of translational …, 2022 - Springer
In recent years, there has been a greater emphasis on the impact of microbial populations
inhabiting the gastrointestinal tract on human health and disease. According to the …
inhabiting the gastrointestinal tract on human health and disease. According to the …
MiRNA-based therapeutic intervention of cancer
S Naidu, P Magee, M Garofalo - Journal of hematology & oncology, 2015 - Springer
MicroRNAs (miRNAs) are important modulators of eukaryotic gene expression. By targeting
protein coding transcripts, miRNAs influence the cellular transcriptome and proteome, thus …
protein coding transcripts, miRNAs influence the cellular transcriptome and proteome, thus …
Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9
E Rodriguez, K Boelaars, K Brown… - Nature …, 2021 - nature.com
Abstract Changes in glycosylation during tumour progression are a key hallmark of cancer.
One of the glycan moieties generally overexpressed in cancer are sialic acids, which can …
One of the glycan moieties generally overexpressed in cancer are sialic acids, which can …
MicroRNA-92a-1–5p increases CDX2 by targeting FOXD1 in bile acids-induced gastric intestinal metaplasia
T Li, H Guo, H Li, Y Jiang, K Zhuang, C Lei, J Wu… - Gut, 2019 - gut.bmj.com
Background and aims Gastric intestinal metaplasia (IM) is common in the gastric epithelium
of patients with chronic atrophic gastritis. CDX2 activation in IM is driven by reflux of bile …
of patients with chronic atrophic gastritis. CDX2 activation in IM is driven by reflux of bile …
The SWI/SNF complex subunit genes: Their functions, variations, and links to risk and survival outcomes in human cancers
S Savas, G Skardasi - Critical reviews in oncology/hematology, 2018 - Elsevier
SWI/SNF is a multiprotein complex essential for regulation of eukaryotic gene expression. In
this article, we review the function and characteristics of this complex and its subunits in …
this article, we review the function and characteristics of this complex and its subunits in …
[HTML][HTML] LncRNA LINC00173 enhances triple-negative breast cancer progression by suppressing miR-490-3p expression
H Fan, J Yuan, X Li, Y Ma, X Wang, B Xu, X Li - Biomedicine & …, 2020 - Elsevier
Long non-coding RNA (lncRNA) LINC00173 has been previously shown to promote
chemoresistance and progression of small-cell lung cancer. Herein, we examine the clinical …
chemoresistance and progression of small-cell lung cancer. Herein, we examine the clinical …
Chromatin and noncoding RNA-mediated mechanisms of gastric tumorigenesis
AKH Loe, L Zhu, TH Kim - Experimental & molecular medicine, 2023 - nature.com
Gastric cancer (GC) is one of the most common and deadly cancers in the world. It is a
multifactorial disease highly influenced by environmental factors, which include radiation …
multifactorial disease highly influenced by environmental factors, which include radiation …
MicroRNA-490-3P targets CDK1 and inhibits ovarian epithelial carcinoma tumorigenesis and progression
S Chen, X Chen, YL Xiu, KX Sun, Y Zhao - Cancer letters, 2015 - Elsevier
Abstract The expression of microRNA-490-3P has been reported to regulate hepatocellular
carcinoma cell proliferation, migration and invasion, and its overexpression significantly …
carcinoma cell proliferation, migration and invasion, and its overexpression significantly …
Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer
Our recent work has shown that DCAF1 (also known as VprBP) is overexpressed in colon
cancer and phosphorylates histone H2AT120 to drive epigenetic gene inactivation and …
cancer and phosphorylates histone H2AT120 to drive epigenetic gene inactivation and …
CircSLC3A2 functions as an oncogenic factor in hepatocellular carcinoma by sponging miR-490-3p and regulating PPM1F expression
H Wang, W Chen, M Jin, L Hou, X Chen, R Zhang… - Molecular cancer, 2018 - Springer
Abstract Background Non-coding RNAs (ncRNAs) have been reported to participate in
tumor progression by regulating gene expression. Previous studies showed that protein …
tumor progression by regulating gene expression. Previous studies showed that protein …