[HTML][HTML] A review of the microbial production of bioactive natural products and biologics

JV Pham, MA Yilma, A Feliz, MT Majid… - Frontiers in …, 2019 - frontiersin.org
A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites,
also known as natural products. Natural products have been a prolific source and an …

Medicinal plants: traditions of yesterday and drugs of tomorrow

A Gurib-Fakim - Molecular aspects of Medicine, 2006 - Elsevier
Plants have provided Man with all his needs in terms of shelter, clothing, food, flavours and
fragrances as not the least, medicines. Plants have formed the basis of sophisticated …

[HTML][HTML] The jasmonate-responsive AP2/ERF transcription factors AaERF1 and AaERF2 positively regulate artemisinin biosynthesis in Artemisia annua L.

ZX Yu, JX Li, CQ Yang, WL Hu, LJ Wang, XY Chen - Molecular Plant, 2012 - cell.com
Plants of Artemisia annua produce artemisinin, a sesquiterpene lactone widely used in
malaria treatment. Amorpha-4, 11-diene synthase (ADS), a sesquiterpene synthase, and …

[HTML][HTML] Exploration of biocompatible AIEgens from natural resources

Y Gu, Z Zhao, H Su, P Zhang, J Liu, G Niu, S Li… - Chemical …, 2018 - pubs.rsc.org
Luminogens with aggregation-induced emission (AIEgens) characteristics have been well
developed and applied in various areas such as bio-imaging, theranostics, organic …

The jasmonate‐responsive AaMYC2 transcription factor positively regulates artemisinin biosynthesis in Artemisia annua

Q Shen, X Lu, T Yan, X Fu, Z Lv, F Zhang… - New …, 2016 - Wiley Online Library
The plant Artemisia annua is well known due to the production of artemisinin, a
sesquiterpene lactone that is widely used in malaria treatment. Phytohormones play …

[图书][B] Alkaloids-Secrets of Life:: Aklaloid Chemistry, Biological Significance, Applications and Ecological Role

T Aniszewski - 2007 - books.google.com
Alkaloids, represent a group of interesting and complex chemical compounds, produced by
the secondary metabolism of living organisms in different biotopes. They are relatively …

[HTML][HTML] The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)

GD Brown - Molecules, 2010 - mdpi.com
The Chinese medicinal plant Artemisia annua L.(Qinghao) is the only known source of the
sesquiterpene artemisinin (Qinghaosu), which is used in the treatment of malaria …

AaMYB1 and its orthologue AtMYB61 affect terpene metabolism and trichome development in Artemisia annua and Arabidopsis thaliana

L Matías‐Hernández, W Jiang, K Yang… - The Plant …, 2017 - Wiley Online Library
The effective anti‐malarial drug artemisinin (AN) isolated from Artemisia annua is relatively
expensive due to the low AN content in the plant as AN is only synthesized within the …

DCEO biotechnology: tools to design, construct, evaluate, and optimize the metabolic pathway for biosynthesis of chemicals

X Chen, C Gao, L Guo, G Hu, Q Luo, J Liu… - Chemical …, 2018 - ACS Publications
Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates …

The roles of AaMIXTA1 in regulating the initiation of glandular trichomes and cuticle biosynthesis in Artemisia annua

P Shi, X Fu, Q Shen, M Liu, Q Pan, Y Tang… - New …, 2018 - Wiley Online Library
The glandular secretory trichomes (GST s) on Artemisia annua leaves have the capacity to
secrete and store artemisinin, a compound which is the most effective treatment for …