Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …

Immunogenic cell death (ICD) has aroused widespread attention because it can reconstruct
a tumor microenvironment and activate antitumor immunity. This study proposes a two‐way …

Both T-cell deprivation and insufficient tumor immunogenicity seriously hinder the efficacy of
immune-mediated tumor destruction in melanoma. In this work, an amphiphilic polyethylene …

Pyroptosis provides a new direction and broad prospects for cancer immunotherapy.
However, the development of a nanoplatform as a pyroptosis inducer is limited, and the …

Notwithstanding immune checkpoint blocking (ICB) therapy has made eminent clinical
breakthroughs, overcoming immunologically “cold” tumors remains challenging. Here, a …

Cancer immunotherapies, such as immune checkpoint blockade and chimeric antigen
receptor (CAR) T cell therapy, have transformed clinical oncology. However, limited patient …

Conventional sonodynamic therapy is unavoidably limited by the tumor microenvironment,
although many sonosensitizers have been developed to improve them to a certain extent …

Oxygen‐deficient molybdenum oxide (MoOX) nanomaterials are prepared as novel
nanosensitizers and TME‐stimulants for ultrasound (US)‐enhanced cancer …

Both hydrogen (H2) and copper ions (Cu+) can be used as anti‐cancer treatments.
However, the continuous generation of H2 molecules and Cu+ in specific sites of tumors is …