Scrub typhus, caused by Orientia tsutsugamushi, is an important and neglected vector-borne
zoonotic disease with an expanding known distribution. The ecology of the disease is …

Peptidoglycan is the predominant stress‐bearing structure in the cell envelope of most
bacteria, and also a potent stimulator of the eukaryotic immune system. Obligate intracellular …

The rickettsioses of the “Far East” or Asia–Australia–Pacific region include but are not limited
to endemic typhus, scrub typhus, and more recently, tick typhus or spotted fever. These …

Trombiculid mites are the vectors of scrub typhus, with infected larval mites (chiggers)
transmitting the causative agent, Orientia tsutsugamushi, during feeding. Co-existence of …

Scrub typhus is a mites-borne rickettsiosis caused by the obligate intracellular Gram-
negative bacterium Orientia tsutsugamushi. The disease is potentially life threatening and is …

Orientia tsutsugamushi, formerly Rickettsia tsutsugamushi, is an obligate intracellular
pathogen that causes scrub typhus, an underdiagnosed acute febrile disease with high …

To replicate within host cells, intracellular bacteria have evolved different strategies to
invade, replicate, persist in, and eventually exit from their hosts. The intracellular lifestyle …

Orientia tsutsugamushi (Ots) is an obligate, intracellular, mite-transmitted human pathogen
which causes scrub typhus. Understanding the diversity of Ots antigens is essential for …

Orientia tsutsugamushi is an obligate intracellular bacterium associated with trombiculid
mites and is the causative agent of scrub typhus, a life-threatening febrile disease. Strain …

Scrub typhus is a febrile disease caused by Orientia tsutsugamushi, transmitted by larval
stage Trombiculid mites (chiggers), whose primary hosts are small mammals. The …