[HTML][HTML] Current understanding of polyphenols to enhance bioavailability for better therapies

M Aatif - Biomedicines, 2023 - mdpi.com
In recent years, plant polyphenols have become a popular focus for the development of
novel functional foods. Polyphenols, a class of bioactive compounds, including flavonoids …

[HTML][HTML] Understanding the prooxidant action of plant polyphenols in the cellular microenvironment of malignant cells: Role of copper and therapeutic implications

M Farhan, A Rizvi - Frontiers in Pharmacology, 2022 - frontiersin.org
Plant derived polyphenolic compounds are considered critical components of human
nutrition and have shown chemotherapeutic effects against a number of malignancies …

[HTML][HTML] Antioxidant vs. prooxidant properties of the flavonoid, kaempferol, in the presence of Cu (II) ions: A ROS-scavenging activity, fenton reaction and DNA damage …

M Simunkova, Z Barbierikova, K Jomova… - International journal of …, 2021 - mdpi.com
Kaempferol is a flavonoid that occurs in tea and in many vegetables and fruits, including
broccoli, cabbage, beans, grapes, apples, and strawberries. The efficacy of Kaempferol has …

[HTML][HTML] Discovery of the involvement in DNA oxidative damage of human sperm nuclear basic proteins of healthy young men living in polluted areas

G Lettieri, G D'Agostino, E Mele, C Cardito… - International Journal of …, 2020 - mdpi.com
DNA oxidative damage is one of the main concerns being implicated in severe cell
alterations, promoting different types of human disorders and diseases. For their …

[HTML][HTML] Current understanding of flavonoids in cancer therapy and prevention

M Farhan, A Rizvi, M Aatif, A Ahmad - Metabolites, 2023 - mdpi.com
Cancer is a major cause of death worldwide, with multiple pathophysiological
manifestations. In particular, genetic abnormalities, inflammation, bad eating habits …

[HTML][HTML] Curcumin and its derivatives induce apoptosis in human cancer cells by mobilizing and redox cycling genomic copper ions

MAI Alhasawi, M Aatif, G Muteeb, MW Alam, ME Oirdi… - Molecules, 2022 - mdpi.com
Turmeric spice contains curcuminoids, which are polyphenolic compounds found in the
Curcuma longa plant's rhizome. This class of molecules includes curcumin …

[HTML][HTML] Inside and beyond color: Comparative overview of functional quality of tomato and watermelon fruits

R Ilahy, I Tlili, MW Siddiqui, C Hdider… - Frontiers in Plant …, 2019 - frontiersin.org
The quali-quantitative evaluation and the improvement of the levels of plant bioactive
secondary metabolites are increasingly gaining consideration by growers, breeders and …

[HTML][HTML] Chemopreventive mechanisms of galangin against hepatocellular carcinoma: A review

D Fang, Z Xiong, J Xu, J Yin, R Luo - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common cancers and has a high
mortality rate in less developed countries, especially in China. Galangin (GA), one of the …

[HTML][HTML] Pomegranate juice anthocyanidins induce cell death in human cancer cells by mobilizing intracellular copper ions and producing reactive oxygen species

M Farhan, A Rizvi, F Ali, A Ahmad, M Aatif… - Frontiers in …, 2022 - frontiersin.org
Anthocyanidins are the most abundant polyphenols in pomegranate juice. This class of
molecules includes Delphinidin (Del), Cyanidin (Cya), and Pelargonidin (Pel). Using …

The molecular mechanisms underlying anti‐inflammatory effects of galangin in different diseases

EHM Hassanein, MS Abd El‐Maksoud… - Phytotherapy …, 2023 - Wiley Online Library
When used as an alternative source of drugs to treat inflammation‐associated diseases,
phytochemicals with anti‐inflammatory properties provide beneficial impacts. Galangin is …