[HTML][HTML] Chronic low grade inflammation in pathogenesis of PCOS

E Rudnicka, K Suchta, M Grymowicz… - International journal of …, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is a one of the most common endocrine disorders, with a
prevalence rate of 5–10% in reproductive aged women. It's characterized by (1) chronic …

[HTML][HTML] Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration

A Więckowska-Gacek, A Mietelska-Porowska… - Ageing research …, 2021 - Elsevier
An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

[HTML][HTML] Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes

F Zatterale, M Longo, J Naderi, GA Raciti… - Frontiers in …, 2020 - frontiersin.org
Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …

Role of C‐reactive protein in diabetic inflammation

J Stanimirovic, J Radovanovic, K Banjac… - Mediators of …, 2022 - Wiley Online Library
Even though type 2 diabetes mellitus (T2DM) represents a worldwide chronic health issue
that affects about 462 million people, specific underlying determinants of insulin resistance …

[HTML][HTML] The importance of animal models in biomedical research: current insights and applications

A Domínguez-Oliva, I Hernández-Ávalos… - Animals, 2023 - mdpi.com
Simple Summary The present review highlights and examines the importance of animal
models in relevant topics concerning current human and animal health. Over the past five …

White adipocyte dysfunction and obesity-associated pathologies in humans

CE Hagberg, KL Spalding - Nature Reviews Molecular Cell Biology, 2024 - nature.com
The prevalence of obesity and associated chronic diseases continues to increase
worldwide, negatively impacting on societies and economies. Whereas the association …

[HTML][HTML] The NLRP3 inflammasome: metabolic regulation and contribution to inflammaging

AK Meyers, X Zhu - Cells, 2020 - mdpi.com
In response to inflammatory stimuli, immune cells reconfigure their metabolism and
bioenergetics to generate energy and substrates for cell survival and to launch immune …

Effect of intermittent fasting diet on glucose and lipid metabolism and insulin resistance in patients with impaired glucose and lipid metabolism: a systematic review …

X Yuan, J Wang, S Yang, M Gao, L Cao… - International journal …, 2022 - Wiley Online Library
The question of whether or not intermittent fasting diets improve the clinical indicators of
glycolipid metabolism remains unclear. This study systematically reviewed the relevant …

[HTML][HTML] Molecular mechanisms of adipogenesis: the anti-adipogenic role of AMP-activated protein kinase

B Ahmad, CJ Serpell, IL Fong… - Frontiers in molecular …, 2020 - frontiersin.org
Obesity is now a widespread disorder, and its prevalence has become a critical concern
worldwide, due to its association with common co-morbidities like cancer, cardiovascular …