Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

Objective To characterise the oral microbiome, gut microbiome and serum lipid profiles in
patients with active COVID-19 and recovered patients; evaluate the potential of the …

Acetaminophen (APAP) overdose is a leading cause of drug-induced liver injury (DILI). The
impact of the gut microbiota and associated metabolites on APAP and liver function remains …

The gut microbiota drives individual sensitivity to excess acetaminophen (APAP)-mediated
hepatotoxicity. It has been reported that the bacterium Akkermansia muciniphila protects …

Non-alcoholic fatty liver disease (NAFLD) is often the hepatic expression of metabolic
syndrome and its comorbidities that comprise, among others, obesity and insulin-resistance …

Lactobacilli and bifidobacteria are an important part of human gut microbiota. Among
numerous benefits, their antioxidant properties are attracting more and more attention …

Nrf2 and NF-κB are important regulators of the response to oxidative stress and
inflammation in the body. Previous pharmacological and genetic studies have confirmed …

Reference standardization was developed to address quantification and harmonization
challenges for high-resolution metabolomics (HRM) data collected across different studies …

It is known that the gut microbiota, the numerically vast and taxonomically diverse microbial
communities that thrive in a symbiotic fashion within our alimentary tract, can affect the …